PHR2589

5-フルオロ-2′-デオキシウリジン

pharmaceutical secondary standard, certified reference material

• 別名: 2′-デオキシ-5-フルオロウリジン, FUDR, フロクスウリジン
• 実験式（ヒル表記法）: C₉H₁₁FN₂O₅
• CAS番号: 50-91-9
• 分子量: 246.19
• Beilstein: 90221
• MDL番号: MFCD00006530
• UNSPSCコード: 41116107
• NACRES: NA.24

特性

• グレード: certified reference material; pharmaceutical secondary standard
• 品質水準: 300
• 認証: traceable to USP 1271008
• 詳細: Pharmaceutical Secondary Standard; Certified Reference Material
• APIファミリー: floxuridine
• フォーム: powder
• CofA: current certificate can be downloaded
• 包装: pkg of 500 mg
• mp: 148 °C (lit.)
• アプリケーション: pharmaceutical small molecule
• 保管温度: 2-30°C
• SMILES記法: OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(F)C(=O)NC2=O
• InChI: 1S/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6+,7+/m0/s1
• InChI Key: ODKNJVUHOIMIIZ-RRKCRQDMSA-N

詳細

詳細

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

アプリケーション

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生物化学的／生理学的作用

チミジル酸シンテターゼの強力なインヒビターとして作用する抗新生物薬。いくつかの手法の中で特に低濃度マイコプラズマ感染により、がん細胞培養中でFUdRに対する耐性が発現する可能性があります。

アナリシスノート

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

その他情報

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301
• 注意書き: P264 - P270 - P301 + P310 - P405 - P501
• 危険有害性の分類: Acute Tox. 3 Oral
• 保管分類コード: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3