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About This Item
実験式（ヒル表記法）:
C10H18O2
CAS番号:
分子量:
170.25
Beilstein:
1721990
MDL番号:
UNSPSCコード:
12352211
PubChem Substance ID:
NACRES:
NA.25
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アプリケーション
cis-2-Decenoic acid may be used to study its cytotoxic effect on the human HepG2 cell line. It has also been used to study its synergistic anti-spirochetal effect.
生物化学的／生理学的作用
cis-2-Decenoic acid is a fatty acid messenger (signaling molecule) produced by Pseudomonas aeruginosa. It possesses anti-biofilm property and converts most of the cells to planktonic (free-swimming) phenotype. cis-2-Decenoic acid retains the susceptibility of the bacteria towards antimicrobial agents. It does not exhibit any toxicity towards human cells and thus, might be used for treating biofilm-associated infections. cis-2-Decenoic acid is considered active even in nano-molar ranges. It mediates the transition of dormant P. aeruginosa and Escherichia coli to their biologically active state without affecting the number of cells. cis-2-Decenoic acid is effective against E. coli and Klebsiella pneumoniae mixed-species biofilms when used along with antimicrobial agents.
包装
底の開いたガラス瓶内容物は内部に挿入され接着された円錐部に入っています。
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2
保管分類コード
10 - Combustible liquids
WGK
WGK 1
適用法令
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Jan Code
19699-25MG:
19699-VAR:
19699-BULK:
試験成績書（COA）
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Frontiers in cellular and infection microbiology, 10, 597517-597517 (2021-02-16)
Blocking virulence is a promising alternative to counteract Pseudomonas aeruginosa infections. In this regard, the phenomenon of cell-cell communication by quorum sensing (QS) is an important anti-virulence target. In this field, fatty acids (FA) have gained notoriety for their role
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