27555

クロキサシリン ナトリウム塩

≥95.0% (HPLC)

• 別名: 3-(o-Chlorophenyl)-5-methyl-4-isoxazolylpenicillin sodium salt, Syntarpen sodium salt
• 実験式（ヒル表記法）: C₁₉H₁₇ClN₃NaO₅S
• CAS番号: 642-78-4
• 分子量: 457.86
• Beilstein: 4103180
• EC Number: 211-390-9
• MDL番号: MFCD00063568
• UNSPSCコード: 51102829
• PubChem Substance ID: 57648259
• NACRES: NA.85

特性

• 由来生物: semisynthetic
• 品質水準: 200
• アッセイ: ≥95.0% (HPLC)
• 形状: powder or crystals
• 不純物: ≤5% Total impurities (anhydrous)
• 色: white to off-white
• 抗生物質活性スペクトル: Gram-positive bacteria
• 作用機序: cell wall synthesis | interferes
• 保管温度: 2-8°C
• SMILES記法: [Na+].Cc1onc(-c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O
• InChI: 1S/C19H18ClN3O5S.Na/c1-8-11(12(22-28-8)9-6-4-5-7-10(9)20)15(24)21-13-16(25)23-14(18(26)27)19(2,3)29-17(13)23;/h4-7,13-14,17H,1-3H3,(H,21,24)(H,26,27);/q;+1/p-1/t13-,14+,17-;/m1./s1
• InChI Key: SCLZRKVZRBKZCR-SLINCCQESA-M

詳細

詳細

Chemical structure: ß-lactam

アプリケーション

Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin is used against staphylococci that produce β-lactamase. It is used to study the role of pH in antibiotic effectiveness and how oxgall, acid, and hydrogen peroxide stress effects the susceptibility of Bifidobacteria.

生物化学的／生理学的作用

Cloxacillin interferes with the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins. This inhibits the necessary cross-linking and leads to autolysis of the bacteria by autolysins.

その他情報

Keep container tightly closed in a dry and well-ventilated place.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)