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Merck
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安全性情報

A9555

Sigma-Aldrich

Monoclonal Anti-Aflatoxin B1 (G1, Q1, B2, G2) antibody produced in mouse

clone AT-B1, ascites fluid

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About This Item

MDL番号:
UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

mouse

品質水準

結合体

unconjugated

抗体製品の状態

ascites fluid

抗体製品タイプ

primary antibodies

クローン

AT-B1, monoclonal

含みます

15 mM sodium azide

テクニック

ELISA: 1:20,000 using aflatoxin B1-BSA

アイソタイプ

IgG1

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

詳細

Monoclonal anti-Aflatoxin B (mouse IgG1 isotype) is 1 derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse.Aflatoxins are a group of naturally occurring fungal toxins (mycotoxins) synthesized by Aspergillus flavus and Aspergillus parasiticus. It is found as contaminants in human and animal food such as corn, peanuts, tree nuts, cottonseed, cereal crops, beans, casssava, milo, sorghum, copra, rice, dried fish and beer.

免疫原

aflatoxin B -KLH conjugate

アプリケーション

Monoclonal Anti-Aflatoxin B1 (G1, Q1, B2, G2) antibody produced in mouse has been used in indirect enzyme linked immunosorbent assay (ELISA) and fluorescence polarization assay.

生物化学的/生理学的作用

Aflatoxin B (AFB) and its metabolites is known to act as potent carcinogens, mutagens and teratogens, in addition to its toxicity. Aflatoxins have been implicated in human hepatocellular carcinoma, outbreaks of aflatoxicosis, Rey′s syndrome, chronic hepatitis and increased mortality from infection in animal husbandry.

ターゲットの説明

Mycotoxins, a group of chemically diverse secondary fungal metabolites, induce a variety of toxic responses in humans and animals when food and feed containing these compounds are ingested. Rapidly quantitating levels of mycotoxin contamination can help reduce exposure to these toxins.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

A9555-.1ML:
A9555-BULK:
A9555-VAR:


試験成績書(COA)

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Screening of Lactobacillus casei strains for their ability to bind aflatoxin B1
Hernandez MA, et al.
Food And Chemical Toxicology, 47(6), 1064-1068 (2009)
Robert J Lee et al.
Scientific reports, 6, 33221-33221 (2016-09-15)
Aflatoxins are mycotoxins secreted by Aspergillus flavus, which can colonize the respiratory tract and cause fungal rhinosinusitis or bronchopulmonary aspergillosis. A. flavus is the second leading cause of invasive aspergillosis worldwide. Because many respiratory pathogens secrete toxins to impair mucociliary
Physicochemical and immunological characterization of chitosan-coated bacteriophage nanoparticles for in vivo mycotoxin modeling
de Andrade CYT, et al.
Carbohydrate Polymers, 185, 63-72 (2018)
Frances A Draughon et al.
Journal of food protection, 45(8), 703-706 (1982-06-01)
Aflatoxin B1 was mixed with eleven concentrations of sodium hydroxide, sodium hypochlorite and ammonium hydroxide. Aflatoxin was quantitated by fluorometric determination and toxicity of aflatoxin treated with NaOH and NH4OH was evaluated by the brine shrimp assay. Detoxified aflatoxin B1
Mycotoxins
Bennett JW, et al.
Clinical Microbiology Reviews, 16(3), 497-497 (2003)

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