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About This Item
実験式（ヒル表記法）:
C17H23NO6
CAS番号:
分子量:
337.37
Beilstein:
2482076
MDL番号:
UNSPSCコード:
12352209
PubChem Substance ID:
NACRES:
NA.26
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製品名
Boc-Glu-OBzl,
アッセイ
≥98% (TLC)
品質水準
フォーム
powder
色
white to off-white
mp
95-99 °C
アプリケーション
peptide synthesis
保管温度
−20°C
SMILES記法
CC(C)(C)OC(=O)N[C@@H](CCC(O)=O)C(=O)OCc1ccccc1
InChI
1S/C17H23NO6/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m0/s1
InChI Key
CVZUKWBYQQYBTF-ZDUSSCGKSA-N
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生物化学的／生理学的作用
Boc-Glu-OBzl is an N-terminal protected amino acid used in solid-phase peptide synthesis (SPPS) to make unique peptides containing glutamate benzyl ester residues.
基質
Substrate for Vitamin K-dependent carboxylation.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
B9003-VAR:
B9003-BULK:
B9003-25G:
B9003-5G:
B9003-1G:
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K H Hsieh et al.
International journal of peptide and protein research, 48(3), 292-298 (1996-09-01)
Side reactions in peptide synthesis indicate steps needing improvement as well as opportunities for structural diversification in combinatorial design. Among the side reactions observed in this study, transesterification of Boc-Glu(OBzl) occurred in TMAH-catalyzed resin attachment, leading to Boc-DKKREE(OMe) in solid-phase
Structure-activity studies on prolactin-releasing peptide (PrRP). Analogues of PrRP-(19-31)-peptide.
Robert G Boyle et al.
Journal of peptide science : an official publication of the European Peptide Society, 11(3), 161-165 (2005-01-07)
An investigation of a series of single replacement analogues of PrRP-(19-31)-peptide has shown that good functional activity was retained when Phe31 was replaced with His(Bzl), Phe(4Cl), Nle, Trp, Cys(Bzl) or Glu(OBzl); when Val28 or Ile25 was replaced with Phg; when
E I Lepist et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 11(1), 43-50 (2000-07-29)
One approach to increase drug stability and to facilitate oral absorption of low bioavailability drugs may be to design oligopeptide ester prodrugs which are stable in the gastrointestinal tract, are transported via the oligopeptide transporter, and finally release the parent
S Romiti et al.
Journal of biochemical and biophysical methods, 11(1), 59-68 (1985-05-01)
Methods are presented that describe alternative protocols for the isolation of rat liver microsomes containing the vitamin K-dependent carboxylase and the procedure in which the solubilized enzyme is assayed. The method for determining the rate of 14CO2 incorporation into low
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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