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リコンビナント
expressed in Sf9 cells
品質水準
フォーム
buffered aqueous solution
比活性
≥1000 units/μg protein
輸送温度
dry ice
保管温度
−70°C
アプリケーション
Phosphodiesterase 3B has been used in a study to evaluate the evidence for biological effects of metformin in operable breast cancer. Phosphodiesterase 3B has also been used in a study to investigate the role of intracellular and intercellular communication in perfusion distribution of erythrocyte-derived ATP.
物性
592アミノ酸～N末端を含むN末端GST融合86 kDaタンパク質
単位の定義
1 unitは、pH 7.4、37°C、1分間に、1.0 pmolの3',5'-cAMPを5'-AMPに変換する酵素量です。
物理的形状
Buffered aqueous solution containing Tris-HCl (pH 8.0), NaCl, KCl, Tween-20, DTT, and glycerol
保管分類コード
12 - Non Combustible Liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
カルタヘナ法
カルタヘナ法
Jan Code
E8909-BULK:
E8909-VAR:
E8909-10UG-PW:
E8909-10UG:
最新バージョンのいずれかを選択してください：
Sirwan Hadad et al.
Breast cancer research and treatment, 128(3), 783-794 (2011-06-10)
Metformin may reduce the incidence of breast cancer and enhance response to neoadjuvant chemotherapy in diabetic women. This trial examined the effects of metformin on Ki67 and gene expression in primary breast cancer. Non-diabetic women with operable invasive breast cancer
Lin Xie et al.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 18(4), 444-454 (2011-12-14)
Here we examined whether the expression of a novel immunoregulatory gene set could be used to predict outcomes in murine models of rapamycin-induced cardiac tolerance, spontaneous hepatic tolerance, and cardiac rejection. The expression of the immunoregulatory gene set was assessed
Randy S Sprague et al.
Microcirculation (New York, N.Y. : 1994), 19(5), 430-439 (2012-07-11)
In complex organisms, both intracellular and intercellular communication are critical for the appropriate regulation of the distribution of perfusion to assure optimal O(2) delivery and organ function. The mobile erythrocyte is in a unique position in the circulation as it
Chimed Jansen et al.
Journal of medicinal chemistry, 56(5), 2087-2096 (2013-02-16)
Trypanosoma brucei cyclic nucleotide phosphodiesterase B1 (TbrPDEB1) and TbrPDEB2 have recently been validated as new therapeutic targets for human African trypanosomiasis by both genetic and pharmacological means. In this study we report the crystal structure of the catalytic domain of
N B Matveeva et al.
Biofizika, 57(5), 832-839 (2012-11-10)
Possible involvement of autocrine factors into the control of motile behavior via a receptor-mediated mechanism was investigated in Physarum polycephalum plasmodium, a multinuclear amoeboid cell with the auto-oscillatory mode of motility. Cyclic adenosine monophosphate (cAMP) and extracellular cAMP-specific phosphodiesterase, its
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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