コンテンツへスキップ
Merck

F4891

Sigma-Aldrich

モノクロナール抗ヤギ/ヒツジ IgG−FITC マウス宿主抗体

clone GT-34, purified from hybridoma cell culture

別名:

モノクロナール抗ヤギ/ヒツジIgG

ログイン組織・契約価格を表示する


About This Item

UNSPSCコード:
12352203
NACRES:
NA.46

由来生物

mouse

品質水準

結合体

FITC conjugate

抗体製品の状態

purified from hybridoma cell culture

抗体製品タイプ

secondary antibodies

クローン

GT-34, monoclonal

形状

buffered aqueous solution

化学種の反応性

sheep, goat, bovine

以下との反応禁止

rat, canine, mouse, rabbit, guinea pig, chicken, horse, pig, feline, human

保管条件

protect from light

テクニック

dot immunobinding: 1:32
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:20
particle immunofluorescence: 1:32

アイソタイプ

IgG1

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

類似した製品をお探しですか? 訪問 製品比較ガイド

詳細

本抗体はヤギIgG1およびIgG2のH鎖に位置するエピト-プと反応します。
Monoclonal Anti-Goat IgG (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. IgG (immunoglobulin G) antibody subtype is a predominant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. IgG is found in four subclasses IgG1, IgG2, IgG3 and IgG4. IgG has a monomeric structure.

特異性

Monoclonal Anti-Goat IgG, FITC Conjugate is immunospecific for goat IgG. The antibody does not react with human, mouse, rat, rabbit, guinea pig, horse, or chicken IgGs.

アプリケーション

Biofile 39 Navya load

生物化学的/生理学的作用

IgG (immunoglobulin G) antibody provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections. IgG antibody participates in complement fixation and opsonization. Goat antibodies against many analytes are widely used in research as primary antibodies in various assay techniques. Second antibodies are that used to detect goat antibodies may lack specificity for goat immunoglobulins, and in many instances will also recognize other immunoglobulins that appear in the preparation being tested. This results in the need for extensive adsorption of the second antibody. Therefore, using a monoclonal antibody to goat IgG that is devoid of a binding capacity to other species can serve as a useful tool in many applications.

物理的形状

0.01M PBS溶液 (pH 7.4, 1%非働化BSA, 15mMアジ化ナトリウム含有)。

保管および安定性

For continuous use, store at 2-8 °C for a maximum of one month. For extended storage, solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify by centrifugation before use.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

適切な製品が見つかりませんか。  

製品選択ツール.をお試しください

保管分類コード

10 - Combustible liquids

WGK

nwg

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

F4891-VAR:
F4891-.5ML:
F4891-.2ML:
F4891-BULK:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Bing Su et al.
The Journal of biological chemistry, 285(7), 4578-4586 (2009-12-19)
SSeCKS/Gravin/AKAP12 ("SSeCKS") encodes a cytoskeletal protein that regulates G(1) --> S progression by scaffolding cyclins, protein kinase C (PKC) and PKA. SSeCKS is down-regulated in many tumor types including prostate, and when re-expressed in MAT-LyLu (MLL) prostate cancer cells, SSeCKS
Alison McDowall et al.
The Journal of clinical investigation, 111(1), 51-60 (2003-01-04)
The adhesion receptors known as integrins perform key functions for hematopoietic cells. The platelet integrin alphaIIbbeta3 is critical in hemostasis, and the beta1 and beta2 integrins on leukocytes have many roles in cell-mediated immunity. Mutations in the beta2 subunit lead
Thomas D Barbour et al.
Kidney international, 89(4), 823-832 (2016-03-01)
C3 glomerulopathy is a complement-mediated renal disease that is frequently associated with abnormalities in regulation of the complement alternative pathway. Mice with deficiency of factor H (Cfh(-/-)), a negative alternative pathway regulator, are an established experimental model of C3 glomerulopathy
Anna L Guildford et al.
Journal of the Royal Society, Interface, 8(58), 641-649 (2010-11-26)
In-stent restenosis is a clinical complication following coronary angioplasty caused by the implantation of the metal device in the atherosclerotic vessel. Histological examination has shown a clear contribution of both inflammatory and smooth muscle cells (SMCs) to the deposition of
Alyssa C Gilmore et al.
Kidney international, 99(2), 396-404 (2020-11-02)
C3 glomerulopathy is characterized by accumulation of complement C3 within glomeruli. Causes include, but are not limited to, abnormalities in factor H, the major negative regulator of the complement alternative pathway. Factor H-deficient (Cfh-/-) mice develop C3 glomerulopathy together with

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

製品に関するお問い合わせはこちら(テクニカルサービス)