M5815

モノクロナール抗ミオゲニン マウス宿主抗体

clone F12B, purified immunoglobulin, buffered aqueous solution

• MDL番号: MFCD01322371
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ELISA (i); IF; IHC (p); IP; WB
• クローン: F12B, monoclonal
• 化学種の反応性: mouse, rat, human
• citations: 16
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1-2 μg/mL using rhabdomyosarcoma tissue sections; immunoprecipitation (IP): 2 μg using 1 mg protein lysate; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1 μg/mL

特性

• 由来生物: mouse
• 品質水準: 200
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: F12B, monoclonal
• フォーム: buffered aqueous solution
• 分子量: antigen 34 kDa
• 化学種の反応性: mouse, rat, human
• テクニック: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1-2 μg/mL using rhabdomyosarcoma tissue sections; immunoprecipitation (IP): 2 μg using 1 mg protein lysate; indirect ELISA: suitable; indirect immunofluorescence: suitable; western blot: 1 μg/mL
• アイソタイプ: IgG1
• UniProtアクセッション番号: P15173
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MYOG(4656) ; mouse ... Myog(17928) ; rat ... Myog(29148)

詳細

詳細

Myogenin belongs to the basic helix-loop-helix (bHLH) superfamily.

Myogenin is a transcription factor present in the nucleus. It possesses an amino-acid rich region and a helix-loop-helix structure. The gene encoding it is localized on human chromosome 1q31-41 and has three exons.

免疫原

リコンビナントラットミオゲニン(アミノ酸30-224)。

アプリケーション

Monoclonal Anti-Myogenin antibody produced in mouse has been used in immunohistochemistry, immunofluorescence and western blotting.

生物化学的／生理学的作用

Myogenin acts as a biomarker in rhabdomyosarcoma (RMS). It has a role in developmental processes, such as hematopoiesis, neurogenesis, myogenesis, tumor cell invasion and metastasis.

Myogenin acts as a regulator during myoblast and skeletal muscle differentiation. It is considered as a definite marker for skeletal muscle differentiation.

物理的形状

PBS溶液 (pH 7.4, 0.08%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable