M7397

L-(−)-リンゴ酸

suitable for cell culture, BioReagent, suitable for insect cell culture

• 別名: (S)-(−)-2-ヒドロキシコハク酸, L-ヒドロキシブタン二酸
• 化学式: HO₂CCH₂CH(OH)CO₂H
• CAS番号: 97-67-6
• 分子量: 134.09
• Beilstein: 1723541
• EC Number: 202-601-5
• MDL番号: MFCD00064213
• UNSPSCコード: 12352205
• PubChem Substance ID: 24897161
• NACRES: NA.75

特性

• 由来生物: microbial
• 品質水準: 200
• 製品種目: BioReagent
• アッセイ: ≥95% (titration)
• 形状: powder
• テクニック: cell culture | insect: suitable; cell culture | mammalian: suitable
• mp: 101-103 °C (lit.)
• 溶解性: water: 100 mg/mL, clear to slightly hazy, colorless
• SMILES記法: O[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1
• InChI Key: BJEPYKJPYRNKOW-REOHCLBHSA-N

詳細

詳細

Malic acid is used as a component of insect tissue culture. It is also useful as an acidulant in soft drinks, jams, fruit and vegetable juices.

アプリケーション

Malic acid has been used:

• to induce basal respiration in mitochondrial cell culture
• to measure the mitochondrial ETC (electron transport chain) activity
• as a component of mitochondrial substrate stock

生物化学的／生理学的作用

Malic acid is a part of cellular metabolism. Its application is recognized in pharmaceutics. It is useful in the treatment of hepatic malfunctioning, effective against hyper-ammonemia. It is used as a part of amino acid infusion. Malic acid also serves as a nanomedicine in the treatment of brain neurological disorders. A TCA (Krebs cycle) intermediate and partner in the malic acid aspartate shuttle.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H315,H319
• 注意書き: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危険有害性の分類: Eye Irrit. 2 - Skin Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves