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使用法
sufficient for 100 fluorometric tests
アプリケーション
pharmaceutical
検出方法
fluorometric
関連疾患
cardiovascular diseases
保管温度
2-8°C
遺伝子情報
human ... PLTP(5360)
詳細
Phospholipid transfer protein (PLTP) is a protein present in normal human plasma. PLTP transfers phospholipids among lipoproteins in plasma.
適合性
Suitable to determine Phospholipid transfer protein (PLTP) activity in plasma or serum (fresh or frozen) as well as other sources of PLTP.
原理
The PLTP Activity Assay Kit includes proprietary substrates to detect PLTP mediated transfer of fluorescent substrate. Transfer activity results in increased fluorescent emission intensity (λEx = 465 nm/λEm = 535 nm) from the assay.
保管分類コード
10 - Combustible liquids
Ryan J Henderson et al.
Drug development and industrial pharmacy, 35(9), 1139-1146 (2009-04-22)
To investigate how different formulations of Amphotericin-B (Amp-B) affect the activity of phospholipid transfer protein (PLTP) when incubated with hyperlipidemic and normolipidemic plasma at physiological temperature (37 degrees C). Six hyperlipidemic and six normolipidemic plasma samples were collected and tested
Axel Schlitt et al.
American journal of nephrology, 27(2), 138-143 (2007-02-20)
Phospholipid transfer protein (PLTP) is mainly involved in high-density lipoprotein (HDL) metabolism. The role of PLTP in atherogenesis is still controversial. We aimed to investigate PLTP activity in hemodialysis (HD) patients, a population which has an increased risk for the
Marta Marchesi et al.
British journal of pharmacology, 164(5), 1460-1468 (2011-04-14)
Besides a significant reduction of low-density lipoprotein (LDL) cholesterol, statins moderately increase high-density lipoprotein (HDL) levels. In vitro studies have indicated that this effect may be the result of an increased expression of apolipoprotein (apo)A-I, the main protein component of
Thomas Gautier et al.
The Journal of biological chemistry, 283(27), 18702-18710 (2008-05-07)
Lipopolysaccharides (LPS) are components of Gram-negative bacteria. The cellular response from the host to LPS is mediated through stepwise interactions involving the lipopolysaccharide-binding protein (LBP), CD14, and MD-2, which produces the rearrangement of TLR4. In addition to LBP, the lipid
Daniela Lakomy et al.
Arteriosclerosis, thrombosis, and vascular biology, 29(11), 1923-1929 (2009-08-15)
Cholesteryl ester transfer protein (CETP) is a target gene for the liver X receptor (LXR). The aim of this study was to further explore this regulation in the monocyte-macrophage lineage and its modulation by lipid loading and inflammation, which are
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