P8390

ピクロトキシニン

• 実験式（ヒル表記法）: C₁₅H₁₆O₆
• CAS番号: 17617-45-7
• 分子量: 292.28
• MDL番号: MFCD00078765
• UNSPSCコード: 41116107
• PubChem Substance ID: 24898746
• NACRES: NA.77

特性

• フォーム: powder
• 品質水準: 200
• SMILES記法: [H][C@@]12OC(=O)[C@]([H])([C@@H]1C(C)=C)[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@@]2([H])[C@]35C
• InChI: 1S/C15H16O6/c1-5(2)7-8-11(16)19-9(7)10-13(3)14(8,18)4-6-15(13,21-6)12(17)20-10/h6-10,18H,1,4H2,2-3H3/t6-,7+,8+,9-,10-,13-,14-,15+/m1/s1
• InChI Key: PIMZUZSSNYHVCU-KBLUICEQSA-N

詳細

詳細

Picrotoxinin is a component of picrotoxin and can be derived from plants. It is a non-nitrogenous compound.

アプリケーション

Picrotoxinin has been used as an agonist of taste 2 receptor member 14 (TAS2R14) to perform an array-based bitter receptor screening assay and to study the effect of calcium buffering and calcium sensor type on its sensitivity.

生物化学的／生理学的作用

Picrotoxinin acts as a potent convulsant.

GABA_A受容体アンタゴニストであり、GABA受容体に結合したCl^-チャネルに結合します。

特徴および利点

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glycine Receptor page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

その他情報

ピクロトキシンの活性成分です。

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H300
• 注意書き: P301 + P310 + P330
• 危険有害性の分類: Acute Tox. 2 Oral
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges