SAB2100200

抗BACE1抗体 ウサギ宿主抗体

affinity isolated antibody

• 別名: 抗β部位APP切断酵素1抗体, 抗ASP2抗体, 抗BACE抗体, 抗FLJ90568抗体, 抗HSPC104抗体
• MDL番号: MFCD03096637
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: IF; IHC; WB
• クローン: polyclonal
• 化学種の反応性: rabbit, bovine, guinea pig, mouse, rat, horse, dog, human
• citations: 6
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: 51 kDa
• 化学種の反応性: rabbit, bovine, guinea pig, mouse, rat, horse, dog, human
• 濃度: 0.5 mg - 1 mg/mL
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProtアクセッション番号: P56817
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... BACE1(23621)

詳細

詳細

β-site APP cleaving enzyme (BACE-1) is known as β-secretase. It consists of an N-terminal signal peptide (SP), a pro-peptide (Pro) domain, a catalytic domain, a transmembrane domain and a C-terminal tail.

BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.

免疫原

Synthetic peptide directed towards the N terminal region of human BACE1

生物化学的／生理学的作用

β-site APP cleaving enzyme (BACE-1) acts as a rate-limiting enzyme of amyloid-β-peptide (Aβ). Overexpression of BACE-1 leads to increased β-secretase activity.

シーケンス

Synthetic peptide located within the following region: GQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTY

物理的形状

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable