SML1335

Pidotimod

≥98% (HPLC)

• 別名: (4R)-3-(5-Oxo-L-prolyl)-1,3-thiazolidine-4-carboxylic acid, (R)-3-((S)-5-Oxopyrrolidine-2-carbonyl)thiazolidine-4-carboxylic acid, (R)-3-[(S)-(5-Oxo-2-pyrrolidinyl) carbonyl]-thiazolidine-4-carboxylic acid, 3-L-Pyroglutamyl-L-thiaziolidine-4carboxylic acid, PGT/1A
• 実験式（ヒル表記法）: C₉H₁₂N₂O₄S
• CAS番号: 121808-62-6
• 分子量: 244.27
• MDL番号: MFCD00867583
• UNSPSCコード: 12352200
• PubChem Substance ID: 329825793
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: powder
• 光学活性: [α]/D -135 to -155°, c = 1 in 6 M HCl
• 色: white to beige
• 溶解性: H₂O: 2 mg/mL, clear (warmed)
• 保管温度: room temp
• SMILES記法: OC([C@@H]1CSCN1C([C@H]2NC(CC2)=O)=O)=O
• InChI: 1S/C9H12N2O4S/c12-7-2-1-5(10-7)8(13)11-4-16-3-6(11)9(14)15/h5-6H,1-4H2,(H,10,12)(H,14,15)/t5-,6-/m0/s1
• InChI Key: UUTKICFRNVKFRG-WDSKDSINSA-N

詳細

生物化学的／生理学的作用

Pidotimod is a dipeptide immunostimulant with biological activity on both the adaptive and the innate immune responses. Pidotimod has been reported to modulate airway epithelial cells functions involved in host-virus interaction possibly through NF-kB activation, promote functional maturation of dendritic cells, and facilitate M2 macrophage polarization and function. Pidotimod has been investigated for use to increase response to recurrent respiratory infections primarily in children.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable