SML1937

SN-6

≥98% (HPLC)

• 別名: 2-[4-(4-Nitrobenzyloxy)benzyl]thiazolidine-4-carboxylic acid ethyl ester, 4-Thiazolidinecarboxylic acid, 2-[[4-[(4-nitrophenyl)methoxy]phenyl]methyl]-, ethyl ester
• 実験式（ヒル表記法）: C₂₀H₂₂N₂O₅S
• CAS番号: 415697-08-4
• 分子量: 402.46
• MDL番号: MFCD06798326
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管条件: desiccated
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: O=C(OCC)C1CSC(CC2=CC=C(OCC3=CC=C([N+]([O-])=O)C=C3)C=C2)N1
• InChI: 1S/C20H22N2O5S/c1-2-26-20(23)18-13-28-19(21-18)11-14-5-9-17(10-6-14)27-12-15-3-7-16(8-4-15)22(24)25/h3-10,18-19,21H,2,11-13H2,1H3
• InChI Key: ZVYIJXLMBWCGHP-UHFFFAOYSA-N

詳細

アプリケーション

SN-6 has been used as a selective Na⁺/Ca⁺⁺ exchanger (NCX) inhibitor to study its neuroprotective effects on axonal injury in mice.

生物化学的／生理学的作用

SN-6 is a selective inhibitor of Na+/Ca++ exchanger (NCX) with some selectivity for the NCX1 isoform.

SN-6 is involved in safeguarding against hypoxia and reoxygenation‐induced cell damage in renal tubular cells.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable