SML3050

Olsalazine sodium

• 別名: Olsalazine sodium, 3,3´-Azobis(6-hydroxybenzoic acid) sodium, 5,5′-Azodisalicylic acid sodium, 5,5′-azobis(salicylic acid) sodium, C.I. Mordant Yellow 5; 3,3′-dicarboxy-4,4′-dihydroxyazobenzene sodium, azodisal sodium
• 実験式（ヒル表記法）: C₁₄H₈N₂O₆ · 2Na
• CAS番号: 6054-98-4
• 分子量: 346.20
• UNSPSCコード: 12352200
• NACRES: NA.24

特性

• アッセイ: ≥98% (HPLC)
• 品質水準: 100
• フォーム: powder
• 色: white to beige
• 溶解性: H₂O: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: [Na+].[Na+].N(=N\c2cc(c(cc2)[O-])C(=O)O)/c1cc(c(cc1)[O-])C(=O)O
• InChI: 1S/C14H10N2O6.2Na/c17-11-3-1-7(5-9(11)13(19)20)15-16-8-2-4-12(18)10(6-8)14(21)22;;/h1-6,17-18H,(H,19,20)(H,21,22);;/q;2*+1/p-2/b16-15+;;
• InChI Key: ZJEFYLVGGFISGT-VRZXRVJBSA-L

詳細

生物化学的／生理学的作用

Olsalazine is an anti-inflammatory drug used in inflammatory bowel disease and ulcerative colitis treatments. It is a pro-drug of 5-aminosalicylic acid (mesalamine) that it is converted by the bacteria in the colon to mesalamine. Olsalazine (5-aminosalicylic acid) is consider as a broad-spectrum anticancer agent. Additionally, olsalazine increases both eEF1A2 and utrophin A levels in in C2C12 myoblasts (relevant to Duchenne muscular dystrophy).

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable