SRP3329

EGF マウス由来

Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• 別名: URG, ウロガストロン
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• 由来生物: mouse
• リコンビナント: expressed in E. coli
• アッセイ: ≥98% (HPLC); ≥98% (SDS-PAGE)
• 形状: lyophilized
• 有効性: ≥1x10^7 units/mg
• 分子量: 6.0 kDa
• 包装: pkg of 500 μg
• 不純物: endotoxin, tested
• UniProtアクセッション番号: P01133
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... EGF(13645)

詳細

詳細

Epidermal growth factor (EGF) is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. The gene encoding this protein is localized on mouse chromosome 3. Recombinant murine EGF is a 6.0kDa globular protein containing 53 amino acid residues, including three intramolecular disulfide-bonds.

生物化学的／生理学的作用

Epidermal growth factor (EGF) has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with transforming growth factor-α (TGF-α) and VGF (vaccinia virus growth factor). Injection of EGF into neonatal and adult rats has been shown to induce neurobehavioral deficits related to schizophrenia.

物理的形状

凍結乾燥品(10 mMリン酸ナトリウム, pH 8.5)。

再構成

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.5-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable