V6879

[Lys⁸]-バソプレッシン

≥98% (HPLC)

• 別名: リジンバソプレッシン, リスプレッシン
• 実験式（ヒル表記法）: C₄₆H₆₅N₁₃O₁₂S₂
• CAS番号: 50-57-7
• 分子量: 1056.22
• EC Number: 200-050-5
• MDL番号: MFCD00133970
• UNSPSCコード: 51111800
• PubChem Substance ID: 24900764
• NACRES: NA.32

特性

• 由来生物: synthetic (organic)
• 品質水準: 200
• 無菌性: non-sterile
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 溶解性: 0.1 M acetic acid: 20 mg/mL, clear, colorless
• UniProtアクセッション番号: P01185
• 輸送温度: ambient
• 保管温度: −20°C
• SMILES記法: CC(O)=O.NCCCCC(NC(=O)C1CCCN1C(=O)C2CSSCC(N)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(Cc4ccccc4)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)N2)C(=O)NCC(N)=O
• InChI: 1S/C46H65N13O12S2.C2H4O2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34;1-2(3)4/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69);1H3,(H,3,4)
• InChI Key: NKWAIKZITYLOMT-UHFFFAOYSA-N
• 遺伝子情報: human ... AVP(551)

詳細

Amino Acid Sequence

Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 [Disulfide Bridge: 1-6]

アプリケーション

[Lys⁸]-Vasopressin was used as a test compound in quantitative analysis of peptides and proteins by using on-line capillary isoelectric focusing-mass spectrometry.The product was used for studying the coupling of a polymer-based microchip electrophoresis to MALDI-TOF MS by using rotating ball interface.

生物化学的／生理学的作用

ブタ、有袋類に存在するバソプレッシンの主要型です。Arg⁸-バソプレッシンよりも血管収縮性と抗利尿作用が低くなっています。

[Lys⁸]-Vasopressin also refers as Lysine vasopressin or Lyspressin is the predominant form of vasopressin present in pigs and marsupials. It antagonizes the amnesia in rats. Lyspressin can also induce resistance to extinction of active avoidance behaviour.

調製ノート

2 mg of [Lys8]-Vasopressin dissolves in 0.1 mL, 0.1M HOAc to yield a clear, colorless solution.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Gloves