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product name
Astec®CHIROBIOTIC®RキラルHPLCカラム, 5 μm particle size, L × I.D. 15 cm × 2.1 mm
物質
stainless steel column
品質水準
詳細
HPLC column
製品種目
Astec®
包装
pkg of 1 ea
メーカー／製品名
Astec®
パラメーター
0-45 °C temperature
241 bar pressure (3500 psi)
テクニック
HPLC: suitable
LC/MS: suitable
L × 内径
15 cm × 2.1 mm
マトリックス
high-purity silica gel particle platform
fully porous particle
マトリックス活性基
ristocetin A glycopeptide phase
粒径
5 μm
ポアサイズ
100 Å
operating pH range
3.5-6.8
分離法
chiral
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詳細
CHIROBIOTIC® Rは、高純度シリカ粒子に共有結合したリストセチンA糖ペプチドを基礎とし、アニオン性化合物のエナンチオマーに対して特に適用性があります。CHIROBIOTIC® Rにおける選択性は有機修飾剤に強く関係し、大きなマージンによるアルコールタイプの移動相が好まれます。
CHIROBIOTIC FAQ
CHIROBIOTIC参考文献一覧
キラル製品文献
- 結合相：リストセチンA
- 操作pH範囲：3.5～6.8
- 粒径：5、10または16 μm
- 孔径：100 Å
CHIROBIOTIC FAQ
CHIROBIOTIC参考文献一覧
キラル製品文献
アプリケーション
- Sensitive determination of D-lactic acid and L-lactic acid in urine by high-performance liquid chromatography-tandem mass spectrometry.: This study demonstrates the application of the Astec CHIROBIOTIC R Chiral HPLC Column in the sensitive determination of D-lactic acid and L-lactic acid in urine samples using HPLC-MS/MS. This highlights its utility in clinical and biomedical research for the analysis of chiral molecules in biological fluids (Henry et al., 2012).
- New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This research utilizes the Astec CHIROBIOTIC R Chiral HPLC Column to develop a method for the chiral separation and determination of warfarin enantiomers. It underscores the column′s application in pharmaceutical analysis, particularly in the study of chiral drug enantiomers (Malakova et al., 2009).
法的情報
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Enzyme-catalyzed synthesis of (R)- and (S)-3-hydroxy-3-(10-alkyl-10H-phenothiazin-3-yl)propanoic acids
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 21 (3), 365-373 (2010)
H Henry et al.
Biomedical chromatography : BMC, 26(4), 425-428 (2011-08-16)
D-lactic acid in urine originates mainly from bacterial production in the intestinal tract. Increased D-lactate excretion as observed in patients affected by short bowel syndrome or necrotizing enterocolitis reflects D-lactic overproduction. Therefore, there is a need for a reliable and
P Dehouck et al.
Journal of chromatography. A, 1010(1), 63-74 (2003-09-25)
Erythromycin is a mixture of macrolide antibiotics produced by Saccharopolyspora erythreas during fermentation. A new method for the analysis of erythromycin by liquid chromatography has previously been developed. It makes use of an Astec C18 polymeric column. After validation in
Enzyme-catalyzed synthesis of (R)- and (S)-3-heteroaryl-3-hydroxy-propanoic acids and their derivatives
Brem, Jurgen, et al.
Tetrahedron Asymmetry, 20 (4), 489-496 (2009)
G Bellucci et al.
Chirality, 6(3), 207-212 (1994-01-01)
The rabbit liver microsomal biotransformation of alpha-methylstyrene (1a), 2-methyl-1-hexene (1b), 2,4,4-trimethyl-1-pentene (1c), and 1,3,3-trimethyl-1-butene (1d) has been investigated with the aim at establishing the enantioface selection of the cytochrome P-450-promoted epoxidation of the double bond and the enantioselectivity of microsomal
プロトコル
Rapid, simple, reproducible chiral separation and quantification of L- and D-lactic acid enantiomers using Supelco’s Astec CHIROBIOTIC® R chiral column and tandem MS.
Chromatograms
application for HPLCapplication for HPLCライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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