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関連製品資料

• Biochromatography Portfolio

  Bulk Resin, Membranes and Prepacked Columns

• Chromatography Purification Selection

  Protein A Affinity Chromatography Options

• Eshmuno^® CMX Resin

  A highly selective mixed mode chromatography resin for difficult to purify mAbs, ADCs and fusion proteins

• Eshmuno^® CP‑FT Resin

  A cation exchange resin specifically developed for the flow-through removal of aggregates using frontal chromatography

• Eshmuno^® CPS

  High capacity and salt tolerance for recombinant protein purification

• Eshmuno^® CPX

  Efficient impurity removal and strong binding capacity at high flow rates

• Eshmuno^® HCX Media

  New, high salt-tolerant multi-mode chromatography resin

• Eshmuno^® S Resin for Superior Downstream mAB Purification

  For superior downstream mAB purification

• Eshmuno^® Q Resin for Efficient AEX Chromatography

  Eshmuno® Q resin is a strong anion exchange (AEX) resin, coupling our renowned tentacle structure with a hydrophilic polyvinyl ether base matrix

• Fractogel^® Chromatography Resin

  Fractogel® resins consist of synthetic methacrylate based polymeric beads providing excellent pressure stability resulting in high flow rates

• Robocolumn^® and Minichrom Chromatography Columns

  Small-scale prepacked chromatography columns for rapid process development, method optimization, parameter screening and sample preparation

• Animation: Separation of Low or Too High DAR Antibody Drug Conjugate Species

  A highly selective mixed mode chromatography resin for difficult to purify mAbs, ADCs and fusion proteins.

• mAbsizer™ Calculator

  The mAbsizer™ Calculator estimates the quantity of MilliporeSigma products required to express, purify, and formulate a mAb effectively.

• Viral Clearance in Antibody Purification Using Tentacle Ion Exchangers

  Manufacturers strive toward cost-effective purification of target molecules and a high level of confidence that their biologics are safe and not compromised by the presence of endogenous retrovirus-like particles or adventitious viruses.

• Bioprocessing Technology Trends of RNA-based Therapeutics and Vaccines

  This article reviews the current dynamics in the RNA therapeutics/vaccines market as well as differences between small-interfering RNA (siRNA), RNA interference (RNAi), microRNA (miRNA), and messenger RNA (MRNA).

• RNA-Based Therapeutics and Vaccines

  New Technologies Are Emerging to Overcome Challenges Associated with Toxicity and Drug Delivery.

• ADC Separation Using a Mixed Mode Cation Exchange Chromatography Step in a mAb Process

  The aim of this technical note is to provide a description of the steps followed and considerations taken during the development of antibody drug conjugate separation using a mixed mode cation exchange chromatography step.

• Intensified Polishing Using Single-pass Tangential Flow Filtration (SPTFF) with Anion Exchange Chromatography

  The bioprocessing industry is interested in Next Generation Processes with higher flexibility, lower costs, and higher product quality.

• Eshmuno^® CMX Application Note on Glycovariant Separation Including for COVID-19

  The aim of this technical note is to provide a description of the capture and subsequent purification of glycoproteins.

• Development Strategy for a Cation Exchange (CEX) Chromatography Step in a Monoclonal Antibody (mAb) Process

  The aim of this technical note is to provide a description of the steps followed and considerations taken during the development of a CEX chromatography step in a mAb process.