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Merck
모든 사진(3)

문서

159530

Sigma-Aldrich

2-Bromo-4′-methylacetophenone

90%

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About This Item

Linear Formula:
CH3C6H4COCH2Br
CAS Number:
Molecular Weight:
213.07
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

90%

bp

105 °C/0.1 mmHg (lit.)

mp

45-49 °C (lit.)

저장 온도

2-8°C

SMILES string

Cc1ccc(cc1)C(=O)CBr

InChI

1S/C9H9BrO/c1-7-2-4-8(5-3-7)9(11)6-10/h2-5H,6H2,1H3

InChI key

KRVGXFREOJHJAX-UHFFFAOYSA-N

일반 설명

2-Bromo-4′-methylacetophenone is an α-bromoketone.

애플리케이션

2-Bromo-4′-methylacetophenone was used in the general fluorous thiol quenching method. It was also used in the preparation of hydroxyquinolinone and N-derivatized carboxamides.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

235.4 °F - closed cup

Flash Point (°C)

113 °C - closed cup

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Use of fluorous silica gel to separate fluorous thiol quenching derivatives in solution-phase parallel synthesis
Zhang W, et al.
Tetrahedron, 58(20), 3871-3875 (2002)
Miroslav Soural et al.
Journal of combinatorial chemistry, 9(5), 793-796 (2007-08-07)
A highly efficient solid-phase synthesis of 2-substituted-3-hydroxy-4(1H)-quinolinone-7-carboxamides was developed using anthranilates and bromoketones as the key synthons. Primary amines immobilized to an acid-cleavable BAL linker were acylated with 1-methyl-2-aminoterephtalate. After cleavage of the methyl ester, bromoketones were used to form
Hana Elshaflu et al.
Frontiers in chemistry, 6, 247-247 (2018-07-19)
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