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Merck
모든 사진(1)

주요 문서

261696

Sigma-Aldrich

Methyl phenyl sulfoxide

≥97%

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About This Item

Linear Formula:
CH3SOC6H5
CAS Number:
Molecular Weight:
140.20
Beilstein:
1904976
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

≥97%

양식

crystals

refractive index

n20/D 1.5775 (lit.)

bp

139-140 °C/14 mmHg (lit.)

mp

26-29 °C (lit.)

작용기

sulfoxide

저장 온도

2-8°C

SMILES string

CS(=O)c1ccccc1

InChI

1S/C7H8OS/c1-9(8)7-5-3-2-4-6-7/h2-6H,1H3

InChI key

JXTGICXCHWMCPM-UHFFFAOYSA-N

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일반 설명

(R)-methyl phenyl sulfoxide is an important pharmaceutical intermediate.

애플리케이션

Methyl phenyl sulfoxide has been used in the synthesis of:
  • isotopically labelled 1, 3-dithiane, a useful labeled synthon
  • nelfinavir, potent HIV-protease inhibitor
  • sulfoximines and in studies on solvent-water partitioning

픽토그램

CorrosionExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

186.8 °F - closed cup

Flash Point (°C)

86 °C - closed cup

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

이미 열람한 고객

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M H Abraham et al.
Journal of pharmaceutical sciences, 83(8), 1085-1100 (1994-08-01)
A general linear solvation energy equation has been used to analyze published partition coefficients in the systems water-octanol (613 solutes), water-hexadecane (370 solutes), water-alkane (200 solutes), and water-cyclohexane (170 solutes). The descriptors used in the equation are R2, an excess
Sadagopan Raghavan et al.
The Journal of organic chemistry, 75(2), 498-501 (2009-12-17)
An asymmetric synthesis of nelfinavir is described starting from acrolein and (S)-methyl phenyl sulfoxide. The key features include (a) stereoselective preparation of a beta-protected amino-gamma,delta-unsaturated sulfoxide by the reaction of an alpha-sulfinyl carbanion with an unsaturated t-butyl sulfinylimine, (b) stereoselective
Aldrichimica Acta, 18, 3-3 (1985)
Nathalie Sauvonnet et al.
The Journal of cell biology, 168(1), 155-163 (2004-12-30)
Endocytosis is critical for many cellular functions. We show that endocytosis of the common gammac cytokine receptor is clathrin independent by using a dominant-negative mutant of Eps15 or RNA interference to knock down clathrin heavy chain. This pathway is synaptojanin
T Egawa et al.
The Journal of biological chemistry, 275(45), 34858-34866 (2000-08-18)
Reaction of ferric native myoglobin (Mb) with hydrogen peroxide (H(2)O(2)) was studied by the aid of stopped-flow rapid-scan spectrophotometry. In contrast to the results in previous studies where compound I was reported to be undetectable, both sperm whale and horse

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