657697

(1R,1′R,2S,2′S)-DuanPhos

• 동의어(들): (1R,1′R,2S,2′S)-2,2′-Di-tert-butyl-2,3,2′,3′-tetrahydro-1H,1′H-(1,1′)biisophosphindolyl
• 실험식(Hill 표기법): C₂₄H₃₂P₂
• CAS Number: 528814-26-8
• Molecular Weight: 382.46
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24884305
• NACRES: NA.22

속성

• 광학 활성: [α]20/D +18°, c = 1 in chloroform
• Quality Level: 100
• mp: 214-246 °C
• SMILES string: CC(C)(C)P1Cc2ccccc2C1C3P(Cc4ccccc34)C(C)(C)C
• InChI: 1S/C24H32P2/c1-23(2,3)25-15-17-11-7-9-13-19(17)21(25)22-20-14-10-8-12-18(20)16-26(22)24(4,5)6/h7-14,21-22H,15-16H2,1-6H3/t21-,22-,25-,26-/m1/s1
• InChI key: HCBRTCFUVLYSKU-SAZLYLDSSA-N

설명

일반 설명

(1R,1′R,2S,2′S)-DuanPhos is an electron-rich chiral phosphine ligand mainly for transition metal catalyzed asymmetric hydrogenation.

애플리케이션

Chiral Quest Phosphine Ligands for Asymmetric Hydrogenation

Catalytic ligand used for:

• Stereoselective synthesis of cyano-substituted dihydropyrroles by annulation of cyanoallenes
• Rhodium-catalyzed intermolecular enantioselective hydroacylation of alkynes to give alpha- and beta-substituted unsaturated ketones by kinetic resolution
• Stereoselective preparation of β-amino nitriles via rhodium-catalyzed asymmetric hydrogenation of amino acrylonitriles
• Stereoselective preparation of anti-1,3-amino alcohols via rhodium-catalyzed asymmetric hydrogenation of β-ketoenamide intermediates
• Stereoselective preparation of acetylaminoindane via rhodium-catalyzed asymmetric hydrogenation of acetylaminoindene

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable