688495

(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline

97%

• 동의어(들): (4S)-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-4,5-dihydrooxazole
• 실험식(Hill 표기법): C₂₅H₂₆NOP
• CAS Number: 148461-16-9
• Molecular Weight: 387.45
• MDL number: MFCD09998277
• UNSPSC 코드: 12352005
• PubChem Substance ID: 329761168
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 97%
• 양식: solid
• 광학 활성: [α]22/D -57.0°, c = 1 in chloroform
• mp: 111-116 °C
• 작용기: ether; phosphine
• 저장 온도: −20°C
• SMILES string: CC(C)(C)[C@@H]1N=C(C2=CC=CC=C2P(C3=CC=CC=C3)C4=CC=CC=C4)OC1
• InChI: 1S/C25H26NOP/c1-25(2,3)23-18-27-24(26-23)21-16-10-11-17-22(21)28(19-12-6-4-7-13-19)20-14-8-5-9-15-20/h4-17,23H,18H2,1-3H3/t23-/m1/s1
• InChI key: DMOLTNKQLUAXPI-HSZRJFAPSA-N

설명

일반 설명

The product is a phosphinooxazoline (PHOX) ligand introduced by Pfaltz and coworkers. These non-symmetrical modular P,N-ligands are particularly useful in cases where double bond migration leads to undesired products or mixtures of isomers.

애플리케이션

(S)-4-tert-Butyl-2-[2-(diphenylphosphino)phenyl]-2-oxazoline can be used as a ligand for enantioselective Heck reaction without any C=C double bond migration byproduct. It can also be used in a rhodium(I)-catalyzed enantioselective desymmetrization reaction of meso-3,5-dimethyl glutaric anhydride, to form substituted syn-deoxypolypropionate fragments in a single transformation.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)