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Merck
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주요 문서

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713783

Sigma-Aldrich

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol

2,000

동의어(들):

Polyethylene glycol, α,ω-Bis-NHS-PEG, Di(N-succinimidyl) PEG-diacid, PEG-bis(N-succinimidyl succinate)

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About This Item

CAS Number:
186020-53-1
MDL number:
MFCD03792507
UNSPSC 코드:
12162002
NACRES:
NA.22

Quality Level

100

형태

powder

분자량

average Mn 2,000

반응 적합성

reagent type: cross-linking reagent

Ω-끝

NHS ester

α-끝

NHS ester

저장 온도

−20°C

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일반 설명

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is a cross-linking reagent.

애플리케이션

O,O′-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol (NHS-PEG-NHS) is suitable reagent used in the covalent conjugation of peanut agglutinin and anticarcinoembryonic antigen antibodies (αCEA) tumor-targeting ligands to near-infrared (NIR)fluorescent superparamagnetic iron oxide (IO)- human serum albumin (HSA) nanoparticles. It is suitable reagent used in the synthesis of novel series of mesoporous silica nanoparticles with different pore sizes, useful for high loading and controlled release of short oligonucleotides.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
BCCH6857
BCCG4340
BCCC7724
BCCC2725
BCCB7092

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Jixi Zhang et al.
Dalton transactions (Cambridge, England : 2003), 43(10), 4115-4126 (2014-01-25)
Aimed at high loading and controlled release of oligonucleotides with short sequences of base-pairs, a novel series of mesoporous silica nanoparticles with three different pore sizes (3.5-5.0 nm) but the same cleavable surface linkers (MSN-Linker-Cys) were synthesized. The small particle
Enav Corem-Salkmon et al.
International journal of nanomedicine, 7, 5517-5527 (2012-11-01)
Colon cancer is one of the major causes of death in the Western world. Early detection significantly improves long-term survival for patients with the disease. Near- infrared (NIR) fluorescent nanoparticles hold great promise as contrast agents for tumor detection. NIR

문서

Polyethylene Glycol Building Blocks for PEGylation

Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers numerous advantages.

Tailoring Collagen-Based Matrices for Regenerative Medicine and Tissue Engineering

Collagen molecules play a critical role in tissue architecture and strength, and in cell-matrix interactions as insoluble ligands to regulate the diverse phenotypic activities of cells.

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

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