767840

Zinc difluoromethanesulfinate

95%

• 동의어(들): Bis(((difluoromethyl)sulfinyl)oxy)zinc, 1,1-difluoro-methanesulfinic acid zinc salt (2:1), Baran difluoromethylation reagent, DFMS
• 실험식(Hill 표기법): C₂H₂F₄O₄S₂Zn
• CAS Number: 1355729-38-2
• Molecular Weight: 295.55
• MDL number: MFCD23134675
• UNSPSC 코드: 12352103
• PubChem Substance ID: 329767342
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 95%
• 양식: solid
• 반응 적합성: reaction type: C-C Bond Formation; reaction type: Fluorinations; reagent type: catalyst; reaction type: C-H Activation; reagent type: diversification reagent
• 작용기: fluoro; sulfinic acid
• 저장 온도: 2-8°C
• SMILES string: FC(F)S(=O)O[Zn]OS(=O)C(F)F
• InChI: 1S/2CH2F2O2S.Zn/c2*2-1(3)6(4)5;/h2*1H,(H,4,5);/q;;+2/p-2
• InChI key: UGEYAPVLXKEKMP-UHFFFAOYSA-L

설명

일반 설명

Material is complexed with up to 1 equivalent of ZnCl₂

Zinc difluoromethanesulfinate is a reagent widely used to incorporate difluoromethyl functionality onto biologically significant structural motifs. It is used to difluoromethylate compounds such as heteroarenes, thiols, enones, and α, β‐unsaturated carboxylic acids.

애플리케이션

Zinc difluoromethanesulfinate (DFMS) is part of a zinc sulfinate toolbox developed by Phil Baran for the simple and rapid diversification of heterocycles.†

Practical and Innate Carbon-Hydrogen Functionalization of Heterocycles

DFMS is a new reagent for direct difluoromethylation of organic substrates via a radical process. This mild, operationally simple, chemoselective, and scalable difluoromethylation method is compatible with a range of nitrogen-containing heteroarene substrates of varying complexity as well as select classes of conjugated p−systems and thiols.†

A New Reagent for Direct Difluoromethylation

Learn More at the Professor and Product Portal of Professor Phil S. Baran.

결합

Frequently Asked Questions are available for this Product.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable