900847

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• 동의어(들): Carboxyl sulfonyl fluoride TMS-alkyne, Probe building block
• 실험식(Hill 표기법): C₁₂H₁₃FO₄SSi
• CAS Number: 2088828-92-4
• Molecular Weight: 300.38
• UNSPSC 코드: 12352106
• NACRES: NA.22

속성

• 분석: ≥95%
• 양식: powder or crystals
• 저장 온도: −20°C
• SMILES string: OC(C1=CC(C#C[Si](C)(C)C)=C(S(F)(=O)=O)C=C1)=O

설명

애플리케이션

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

기타 정보

Technology Spotlight: Trifunctional Probe Building Blocks
Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable