900863

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol

≥95%

• 동의어(들): 3-(3-Butyn-1-yl)-3H-diazirine-3-ethanol, Hydroxyl diazirine alkyne, Probe building block
• 실험식(Hill 표기법): C₇H₁₀N₂O
• CAS Number: 1450754-41-2
• Molecular Weight: 138.17
• MDL number: MFCD29918290
• UNSPSC 코드: 12352200
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 형태: liquid
• density: 1.08 g/mL
• 저장 온도: −20°C
• SMILES string: OCCC1(N=N1)CCC#C

설명

애플리케이션

2-(3-But-3-ynyl-3H-diazirin-3-yl)-ethanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

기타 정보

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Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable