900864

4-(Bromomethyl)-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

• 동의어(들): Bromo sulfonyl fluoride TMS-alkyne, Probe building block
• 실험식(Hill 표기법): C₁₂H₁₄BrFO₂SSi
• CAS Number: 2088828-99-1
• Molecular Weight: 349.29
• UNSPSC 코드: 12352200
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: ≥95%
• 형태: powder or crystals
• 재고 정보: available only in USA
• 저장 온도: −20°C
• SMILES string: O=S(C(C(C#C[Si](C)(C)C)=C1)=CC=C1CBr)(F)=O

설명

애플리케이션

Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

기타 정보

• 1.Technology Spotlight: Trifunctional Probe Building Blocks
• 2.Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

안전성 정보

• 픽토그램: GHS02
• 신호어: Danger
• 유해 및 위험 성명서: H242
• 예방조치 성명서: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable