700025P

7β,27-dihydroxycholesterol

Avanti Research^™ - A Croda Brand

• 동의어(들): (3β,7β,25R)-Cholest-5-ene-3,7,26-triol
• 실험식(Hill 표기법): C₂₇H₄₆O₃
• CAS Number: 240129-43-5
• Molecular Weight: 418.65
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 양식: powder
• 포장: pkg of 1 × 1 mg (700025P-1mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: [H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=C[C@@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC[C@@H](C)CO
• InChI: 1S/C27H46O3/c1-17(16-28)6-5-7-18(2)21-8-9-22-25-23(11-13-27(21,22)4)26(3)12-10-20(29)14-19(26)15-24(25)30/h15,17-18,20-25,28-30H,5-14,16H2,1-4H3/t17-,18-,20+,21-,22+,23+,24+,25+,26+,27-/m1/s1
• InChI key: RXMHNAKZMGJANZ-BMOLSTJGSA-N

설명

일반 설명

7β,27-dihydroxycholesterol is a substrate for enzyme 11β-hydroxysteroid dehydrogenases (11β-HSDs).

애플리케이션

7β,27-dihydroxycholesterol has been used as an internal standard in ultra-performance liquid chromatography -tandem mass spectrometer (UPLC-MS/MS). It has also been used as a substrate for 11β-hydroxysteroid dehydrogenases (11β-HSDs) in human embryonic kidney cells (HEK293).

생화학적/생리학적 작용

7β,27-dihydroxycholesterol (7β27OHC) is a retinoid-related orphan receptor γ (RORγ) ligand. 7β27OHC favors smoothened (Smo) functionality.

포장

5 mL Amber Glass Screw Cap Vial (700025P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids