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Merck
모든 사진(2)

주요 문서

850356C

Avanti

4ME 16:0 PC

Avanti Research - A Croda Brand

동의어(들):

1,2-di-(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholine; PC(16:0(3me,7me,11me,15me)/16:0(3me,7me,11me,15me))

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About This Item

실험식(Hill 표기법):
C48H96NO8P
CAS Number:
Molecular Weight:
846.25
UNSPSC 코드:
51191904
NACRES:
NA.25

설명

1,2-diphytanoyl-sn-glycero-3-phosphocholine, chloroform

분석

>99% (TLC)

형태

liquid

포장

pkg of 1 × 2.5 mL (850356C-25mg)
pkg of 1 × 20 mL (850356C-500mg)
pkg of 2 × 4 mL (850356C-200mg)

제조업체/상표

Avanti Research - A Croda Brand

농도

10 mg/mL (850356C-25mg)
25 mg/mL (850356C-200mg)
25 mg/mL (850356C-500mg)

배송 상태

dry ice

저장 온도

−20°C

일반 설명

4ME 16:0 PC/DPhPC (1,2-diphytanoyl-sn-glycero-3-phosphocholine is a synthetic lipid. It has ester linkages between acyl chains and glycerol backbone and also between the headgroup and glycerol backbone. This neutral lipids possess high steric asymmetry. It remains in fluid or viscous liquid crystalline state over a wide range of temperature.
Lipids containing diphytanoyl fatty acid chains have been used to produce stable planar lipid membranes (see References). Diphytanoyl phosphatidylcholine does not exhibit a detectable gel to liquid crystalline phase transition from -120°C to +120°C.The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis.

애플리케이션

4ME 16:0 PC is suitable for use:
  • to study its phase behaviour and its interactions with the representative antimicrobial peptide PGLa from Xenopus laevis (peptidyl-glycylleucine-carboxyamide
  • to improve the mechanical stability of planar lipid bilayer membrane
  • to prepare giant unilamellar vesicles (GUVs)

생화학적/생리학적 작용

4ME 16:0 PC/DPhPC (1,2-diphytanoyl-sn-glycero-3-phosphocholine can be used as a bilayer mimic for electrophysiological measurements. It is stable under mechanical stress but the ester linkages are liable to hydrolysis under acidic or alkaline conditions.

포장

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850356C-500mg)
5 mL Clear Glass Sealed Ampule (850356C-200mg)
5 mL Clear Glass Sealed Ampule (850356C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Formation and characterization of planar lipid bilayer membranes from synthetic phytanyl-chained glycolipids
Baba T, et al.
Biochimica et Biophysica Acta - Biomembranes, 1421(1), 91-102 (1999)
Tim Diederichs et al.
Nature communications, 10(1), 5018-5018 (2019-11-07)
Nanopores are key in portable sequencing and research given their ability to transport elongated DNA or small bioactive molecules through narrow transmembrane channels. Transport of folded proteins could lead to similar scientific and technological benefits. Yet this has not been
Physical properties of bilayer membranes formed from a synthetic saturated phospholipid in n-decane.
W R Redwood et al.
Biochimica et biophysica acta, 233(1), 1-6 (1971-03-09)
Stephanie Tristram-Nagle et al.
Chemistry and physics of lipids, 163(6), 630-637 (2010-05-08)
Diphytanoylphosphatidylcholine (DPhyPC) is a branched chain lipid often used for model membrane studies, including peptide/lipid interactions, ion channels and lipid rafts. This work reports results of volume measurements, water permeability measurements P(f), X-ray scattering from oriented samples, and X-ray and
Chan Cao et al.
Nature communications, 10(1), 4918-4918 (2019-10-31)
Nanopore sensing is a powerful single-molecule approach for the detection of biomolecules. Recent studies have demonstrated that aerolysin is a promising candidate to improve the accuracy of DNA sequencing and to develop novel single-molecule proteomic strategies. However, the structure-function relationship

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