860508P

C8 Ceramide (d18:1/8:0)

Avanti Research^™ - A Croda Brand 860508P, powder

• 동의어(들): N-octanoyl-D-erythro-sphingosine
• 실험식(Hill 표기법): C₂₆H₅₁NO₃
• CAS Number: 74713-59-0
• Molecular Weight: 425.69
• UNSPSC 코드: 12352211
• NACRES: NA.25

속성

• 형태: powder
• 포장: pkg of 1 × 5 mg (860508P-5mg)
• 제조업체/상표: Avanti Research^™ - A Croda Brand 860508P
• 지질 유형: sphingolipids
• 배송 상태: dry ice
• 저장 온도: −20°C
• SMILES string: OC[C@]([H])(NC(CCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C26H51NO3/c1-3-5-7-9-10-11-12-13-14-15-16-18-19-21-25(29)24(23-28)27-26(30)22-20-17-8-6-4-2/h19,21,24-25,28-29H,3-18,20,22-23H2,1-2H3,(H,27,30)/b21-19+/t24-,25+/m0/s1
• InChI key: APDLCSPGWPLYEQ-WRBRXSDHSA-N

설명

일반 설명

C8 Ceramide is a short chain ceramide and is cell permeable.

애플리케이션

C8 Ceramide (d18:1/8:0) has been used as an internal ceramide standard in electrospray ionization. It has also been used as a substrate for ceramide kinase activity assay. It is suitable for use as a substrate for galactocerebrosidase.

생화학적/생리학적 작용

C8 Ceramide has anti-tumor functionality. Synthetic liposomal C8 ceramide inhibits hepatocellular carcinoma (HCC). Addition of exogenous C8 ceramide causes necrosis in hepatocytes by decreasing ATP levels and impairing mitochondrial functionality. C8 ceramide inhibition of serine palmitoyl transferase halts de novo sphingolipid biosynthesis. It also acts as chemotherapeutic agent by increasing the reactive oxygen species in lung cancer cells.

포장

5 mL Amber Glass Screw Cap Vial (860508P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

안전성 정보

• Storage Class Code: 11 - Combustible Solids