C0982

Chlorpromazine hydrochloride

meets USP testing specifications

• 동의어(들): 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil
• 실험식(Hill 표기법): C₁₇H₁₉ClN₂S · HCl
• CAS Number: 69-09-0
• Molecular Weight: 355.33
• Beilstein: 3779989
• EC Number: 200-701-3
• MDL number: MFCD00012654
• UNSPSC 코드: 41116107
• PubChem Substance ID: 24892290
• NACRES: NA.21

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• Agency: USP/NF; meets USP testing specifications
• 분석: 98.0-101.5% dry basis
• 형태: solid
• mp: 194-196 °C
• solubility: water: soluble 50 g/L
• 응용 분야: pharmaceutical (small molecule)
• 저장 온도: room temp
• SMILES string: Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13
• InChI: 1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
• InChI key: FBSMERQALIEGJT-UHFFFAOYSA-N
• 유전자 정보: human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356)

설명

애플리케이션

Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

생화학적/생리학적 작용

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.

Phenothiazine antipsychotic; D₂ dopamine receptor antagonist, H₁ histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301,H330
• 예방조치 성명서: P260 - P264 - P270 - P271 - P284 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 3 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges