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Merck
모든 사진(1)

주요 문서

D0501

Supelco

4-Deoxypyridoxine hydrochloride

analytical standard

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About This Item

실험식(Hill 표기법):
C8H11NO2 · HCl
CAS Number:
Molecular Weight:
189.64
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

생물학적 소스

synthetic (organic)

Quality Level

Grade

analytical standard

분석

≥98%

기술

HPLC: suitable
gas chromatography (GC): suitable

색상

white to yellow

mp

263-265 °C

응용 분야

forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products

형식

neat

저장 온도

−20°C

SMILES string

Cl.Cc1ncc(CO)c(C)c1O

InChI

1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H

InChI key

QZKKOQQIVLXUEI-UHFFFAOYSA-N

일반 설명

4-Deoxypyridoxine hydrochloride is a strong antagonist of vitamin B6.

애플리케이션

4-Deoxypyridoxine hydrochloride analytical standard can be used as follows:
  • Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with mass spectrometric (MS) detection for the impurity analysis of metadoxine drug
  • As an internal standard in the ultra- and high- performance liquid chromatographic analysis of pyridoxine in multivitamin tablet samples coupled with UV, mass spectrometric, and fluorescence detector

기타 정보

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

J Scountzou et al.
Immunopharmacology and immunotoxicology, 11(4), 657-666 (1989-01-01)
We studied the effect of pyridoxine deficiency state on the responses of human lymphocytes to certain mitogenic factors. Deoxypyridoxine (DB6), a potent pyridoxine antagonist, considerably inhibited Bromodeoxyuridine (BrdU) incorporation into the newly synthesized DNA of lymphocytes cultured with Phytohemagglutinin (PHA)
A Trakatellis et al.
Postgraduate medical journal, 68 Suppl 1, S70-S77 (1992-01-01)
Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme was very low. Under the influence of mitogenic stimuli serine hydroxymethyl-transferase activity was induced 5-20-fold. Addition in the cultures of 4-deoxypyridoxine, a
HPLC analysis of vitamin B6 in foods
Ollilainen, V-M
Agricultural and food science, 8(6), 515-619 (1999)
T Yagi et al.
Biochimie, 71(4), 427-438 (1989-04-01)
The intracellular proportion of the pyridoxal 5'-phosphate form of aspartate aminotransferase to the total enzyme in E. coli B cells was determined by a newly devised method, dependent on selective inactivation of the intracellular pyridoxal 5'-phosphate form of the enzyme
T Mizote et al.
Microbiology (Reading, England), 142 ( Pt 10), 2969-2974 (1996-10-01)
Extracts from Escherichia coli K-12 contained two distinct enzymes capable of catalysing the phosphorylation of hydroxymethylpyrimidine (HMP) to HMP monophosphate: pyridoxine kinase (EC 2.7.1.35) and an enzyme that has not previously been genetically analysed, HMP kinase (EC 2.7.1.49). Two distinct

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