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Merck
모든 사진(1)

주요 문서

I3132

Supelco

Indoprofen

analytical standard

동의어(들):

α-Methyl-p-(1-oxo-2-isoindolinyl)benzeneacetic acid

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About This Item

실험식(Hill 표기법):
C17H15NO3
CAS Number:
Molecular Weight:
281.31
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)
veterinary

형식

neat

SMILES string

CC(C(O)=O)c1ccc(cc1)N2Cc3ccccc3C2=O

InChI

1S/C17H15NO3/c1-11(17(20)21)12-6-8-14(9-7-12)18-10-13-4-2-3-5-15(13)16(18)19/h2-9,11H,10H2,1H3,(H,20,21)

InChI key

RJMIEHBSYVWVIN-UHFFFAOYSA-N

유전자 정보

애플리케이션

Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities. Its mode of action involves the inhibition of prostaglandin synthesis.
Indoprofen may be used as an analytical reference standard for the quantification of the analyte in biological samples and pharmaceutical formulations using different chromatography techniques.
Indoprofen is a non-steroidal drug, which can show a range of pharmacological properties such as analgesic and anti-inflammatory activities.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 3 Oral - Carc. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Mitchell R Lunn et al.
Chemistry & biology, 11(11), 1489-1493 (2004-11-24)
Most patients with the pediatric neurodegenerative disease spinal muscular atrophy have a homozygous deletion of the survival motor neuron 1 (SMN1) gene, but retain one or more copies of the closely related SMN2 gene. The SMN2 gene encodes the same
B Lund et al.
British journal of clinical pharmacology, 22(6), 721-724 (1986-12-01)
Multiple dosing four times daily for 7 days of indoprofen 200 mg, a non-steroidal anti-inflammatory drug with a short half-life (t1/2), revealed drug accumulation in eight elderly subjects. This indicates a substantially longer t1/2 (11 h) than that reported in
Da-Qing Jin et al.
Pharmacology, biochemistry, and behavior, 89(3), 404-411 (2008-02-26)
Non-steroidal anti-inflammatory drugs (NSAIDs) have been proposed as a therapeutics to reduce the risk of Alzheimer's disease (AD). The present study shows that the peripheral administration of dexibuprofen (S(+)-isomer ibuprofen), which causes less gastric damage and has better anti-inflammatory effects
David J Hamilton et al.
Pharmaceuticals (Basel, Switzerland), 13(11) (2020-11-07)
Drug discovery programs against the antibacterial target UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) have already resulted in covalent inhibitors having small three- and five-membered heterocyclic rings. In the current study, the reactivity of four-membered rings was carefully modulated to obtain a novel
Determination of the enantiomers of indoprofen in blood plasma by high-performance liquid chromatography after rapid derivatization by means of ethyl chloroformate
Bjorkman S
Journal of Chromatography. B, Biomedical Applications, 339(2), 339-346 (1985)

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