PHR1448
Sulfadimethoxine
Pharmaceutical Secondary Standard; Certified Reference Material
동의어(들):
Sulfadimethoxine, 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C12H14N4O4S
CAS Number:
Molecular Weight:
310.33
Beilstein:
306856
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24
추천 제품
Grade
certified reference material
pharmaceutical secondary standard
Quality Level
Agency
traceable to USP 1626001
API family
sulfadimethoxine
CofA
current certificate can be downloaded
포장
pkg of 500 mg
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
pharmaceutical (small molecule)
형식
neat
저장 온도
2-30°C
SMILES string
COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
InChI
1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI key
ZZORFUFYDOWNEF-UHFFFAOYSA-N
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일반 설명
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Sulfadimethoxine is an long acting sulfonamide antibiotic, commonly used against a broad spectrum of bacterial infections in animals. Its mode of action involves the inhibition of folic acid synthesis in prokaryotes. It is also widely used in veterinary medication to treat coccidiosis in cats and dogs.
애플리케이션
Sulfadimethoxine may be used as a pharmaceutical reference standard for the quantification of the analyte in veterinary formulations using liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
분석 메모
These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
기타 정보
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
각주
To see an example of a Certificate of Analysis for this material enter LRAA2825 in the slot below. This is an example certificate only and may not be the lot that you receive.
관련 제품
제품 번호
설명
가격
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Simultaneous determination of sulfamethoxypyridazine, sulfamethoxazole, sulfadimethoxine and their associated compounds by liquid chromatography.
Nevado JJ, et al.
Analytica Chimica Acta, 442(2), 241-248 (2001)
Small Animal Clinical Pharmacology (2011)
Minjoo Kim et al.
PloS one, 10(3), e0119519-e0119519 (2015-03-18)
Existing data on the association between being overweight and cardiovascular morbidity and mortality risk in adults are inconsistent. We prospectively and longitudinally investigated the effects of weight on arterial stiffness and plasma metabolites in middle-aged subjects (aged 40-55 years). A
Zhe Meng et al.
Food chemistry, 174, 597-605 (2014-12-23)
A novel UPLC-MS/MS method for quantification and confirmation of eight fluoroquinolones, five sulphonamides (SAs) and four acetyled metabolites in milk is developed. Their main fragmentation pathways were presented. The limits of quantification were in the range of 0.01-0.29 μg kg(-1)
Werner Siegmund et al.
British journal of clinical pharmacology, 79(3), 501-513 (2014-09-30)
The rare association of flupirtine with liver injury is most likely caused by reactive quinone diimines and their oxidative formation may be influenced by the activities of N-acetyltransferases (NAT) that conjugate the less toxic metabolite D13223, and by glucuronosyltransferases (UGT)
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