42602

Propionyl-L-carnitine

≥94.0% (HPLC), suitable for LC/MS

• 동의어(들): (2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine
• 실험식(Hill 표기법): C₁₀H₁₉NO₄
• CAS Number: 20064-19-1
• Molecular Weight: 217.26
• MDL number: MFCD00870024
• UNSPSC 코드: 12352209
• PubChem Substance ID: 329756246
• NACRES: NA.26

속성

• 제품명: Propionyl-L-carnitine, ≥94.0% (HPLC)
• Quality Level: 100
• 분석: ≥94.0% (HPLC)
• 양식: powder or crystals
• 광학 활성: [α]/D -23±3°, c = 1 in H₂O
• 기술: LC/MS: suitable
• 불순물: ≤10% water (calcd. from elemental analysis)
• 색상: white to off-white
• 저장 온도: 2-8°C
• SMILES string: [O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O
• InChI: 1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
• InChI key: UFAHZIUFPNSHSL-MRVPVSSYSA-N

설명

일반 설명

Propionyl-L-carnitine (PLC) is a short-chain fatty acid ester derivative of carnitine.

애플리케이션

Propionyl-L-carnitine has been used as a standard in liquid chromatography-tandem mass spectrometry (LC-MS/MS).

생화학적/생리학적 작용

Propionyl-L-carnitine (PLC) plays a key role in lipid and carbohydrate metabolism. It provides substrates to the ischemic muscle for energy production and ATP generation. PLC has the potential to treat severe peripheral arterial disease and chronic heart failure. It is present in high abundance in the urine of patients with methylmalonyl-CoA mutase (MUT) deficiency, together with methylmalonic acid. MUT is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable