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Merck
모든 사진(4)

주요 문서

50046

Sigma-Aldrich

Glycine

≥99.0% (NT), BioUltra

동의어(들):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein:
635782
EC Number:
MDL number:
UNSPSC 코드:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

product name

Glycine, BioUltra, for molecular biology, ≥99.0% (NT)

Grade

for molecular biology

Quality Level

제품 라인

BioUltra

분석

≥99.0% (NT)

형태

crystalline

불순물

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected

무기 잔류물

≤0.05% (as SO4)

손실

≤0.05% loss on drying, HV, 20-26 °C

색상

white

pKa(25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M at 20 °C, clear, colorless

음이온 미량물

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg

양이온 미량물

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
NH4+: ≤200 mg/kg
Na: ≤100 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

NCC(O)=O

λ

1 M in 1 M HCl

UV 흡수

λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.05

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

유전자 정보

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Glycine has been used as a component of the viral extraction mixture for adenovirus viral extraction.

생화학적/생리학적 작용

Glycine is a non-essential amino acid. It is involved in the synthesis of purines, serine and porphyrins. Glycine-gated channels mediate the influx of calcium through cell membranes. It also acts as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. In cancer cells, the synthesis of glycine might be increased due to increased demand for the amino acid.
Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Determining pathogen and indicator levels in class B municipal organic residuals used for land application.
Rhodes ER
Journal of Environmental Quality, 44(1), 265-274 (2015)
F. Cobianchi et al.
Methods in Enzymology, 152, 101-101 (1987)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain
Science, 336(6084), 1040-1044 (2012)
Characterization of in vitro translation products.
R Jagus
Methods in enzymology, 152, 296-304 (1987-01-01)
Alexander Carvajal-González et al.
Brain : a journal of neurology, 137(Pt 8), 2178-2192 (2014-06-22)
The clinical associations of glycine receptor antibodies have not yet been described fully. We identified prospectively 52 antibody-positive patients and collated their clinical features, investigations and immunotherapy responses. Serum glycine receptor antibody endpoint titres ranged from 1:20 to 1:60 000.

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