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Merck
모든 사진(1)

주요 문서

53471

Sigma-Aldrich

FITC-CM-Dextran

average mol wt 70,000

동의어(들):

FITC-CM-Dextran 70, Fluorescein isothiocyanate–Carboxymethyl–Dextran

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About This Item

UNSPSC 코드:
12352116
NACRES:
NA.32

결합

FITC conjugate

Quality Level

양식

powder or crystals

분자량

average mol wt 70,000

구성

carboxymethyl content, 3-7%

라벨링 범위

0.001-0.020 mol/mol FITC glucose

기술

permeability assay: suitable

형광

λex 493 nm; λem 517 nm±5 nm in 0.1 M Tris pH 8.0

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일반 설명

FITC-CM-Dextran, also known as Fluorescein isothiocyanate–Carboxymethyl–Dextran, is an anionic fluorescent probe. The carboxyl group provides the negative charge, which improves the overall permeability of the molecule. It is supplied as a yellow powder that is freely soluble in water and electrolyte solutions. FITC-CM-Dextran is insoluble in most organic samples such as ethanol, methanol, acetone, and chloroform. FITC-CM-Dextran is manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali, whereby O-carboxymethyl groups are introduced along the dextran chain.

애플리케이션

FITC-CM-dextran is used to study drug intake and delivery mechanisms in HeLa cell lines. FITC-CM-Dextran was chosen due to its high water solubility and negative charge. It is also a suitable molecule to be used in encapsulation studies for polymersomal drug delivery systems or Ps DDS. FITC-CM-Dextran is a biocompatible molecule used as a starting material in several pharmaceutical and diagnostic applications.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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