90182

N_α-Tosyl-L-lysine chloromethyl ketone hydrochloride

≥99.0% (AT)

• 동의어(들): (3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone hydrochloride, (3S)-7-Amino-1-chloro-3-tosylamino-2-heptanone hydrochloride, TLCK, Tosyl-L-lysyl-chloromethane hydrochloride
• 실험식(Hill 표기법): C₁₄H₂₁ClN₂O₃S · HCl
• CAS Number: 4272-74-6
• Molecular Weight: 369.31
• Beilstein: 7106867
• EC Number: 224-266-4
• MDL number: MFCD00065395
• UNSPSC 코드: 12352202
• eCl@ss: 32160406
• PubChem Substance ID: 57653369
• NACRES: NA.77

속성

• 생물학적 소스: synthetic
• 분석: ≥99.0% (AT)
• 형태: powder or crystals
• 광학 활성: [α]20/D −7.8±0.5°, c = 2% in H₂O
• 저장 온도: −20°C
• SMILES string: Cl[H].Cc1ccc(cc1)S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl
• InChI: 1S/C14H21ClN2O3S.ClH/c1-11-5-7-12(8-6-11)21(19,20)17-13(14(18)10-15)4-2-3-9-16;/h5-8,13,17H,2-4,9-10,16H2,1H3;1H/t13-;/m0./s1
• InChI key: YFCUZWYIPBUQBD-ZOWNYOTGSA-N

설명

기타 정보

An alkylating reagent that may react with histidine or cysteine residues at the active site of enzymes. Inactivates serine proteases such as trypsin and clostripain . Chymotrypsin is not affected. To prevent proteolytic degradation, a combination of TLCK and TPCK can be used throughout the isolation of proteins, as in the isolation of histones.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves