콘텐츠로 건너뛰기
Merck
모든 사진(4)

주요 문서

A0760

Sigma-Aldrich

L-Azetidine-2-carboxylic acid

≥99%

동의어(들):

(S)-Azetidine-2-carboxylic acid

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C4H7NO2
CAS Number:
Molecular Weight:
101.10
Beilstein:
80680
EC Number:
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.32

Quality Level

분석

≥99%

양식

powder

SMILES string

OC(=O)[C@@H]1CCN1

InChI

1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1

InChI key

IADUEWIQBXOCDZ-VKHMYHEASA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.

애플리케이션

L-Azetidine-2-carboxylic acid has been used as a:
  • collagen synthesis inhibitor
  • protein folding antagonist
  • as a standard in liquid chromatography-mass spectrometry

생화학적/생리학적 작용

Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.
L-Azetidine-2-carboxylic acid is an inhibitor of collagen synthesis that is anti-angiogenic.
L-Azetidine-2-carboxylic acid is an inhibitor of collagen synthesis that is anti-angiogenic. It is a four-membered ring analog of L-proline that causes protein misconstruction when incorporated instead of proline.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number

적합한 버전을 찾을 수 없으신가요?

특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Asmita Ghosh et al.
Cellular and molecular life sciences : CMLS, 76(8), 1605-1621 (2019-01-27)
The proteostasis network (PN) comprises a plethora of proteins that are dedicated to aid in protein folding and maintenance; some with overlapping functions. Despite this, there are multiple pathophysiological states associated with depletion of chaperones. This is counter-intuitive, assuming cells
Azetidine-2-carboxylic acid in garden beets (Beta vulgaris)
Rubenstein E, et al.
Phytochemistry, 67(9), 898-903 (2006)
Kate Samardzic et al.
Amino acids, 51(8), 1221-1232 (2019-07-16)
In addition to the 20 protein amino acids that are vital to human health, hundreds of naturally occurring amino acids, known as non-proteinogenic amino acids (NPAAs), exist and can enter the human food chain. Some NPAAs are toxic through their
Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness
Tye B, et al.
eLife, 8(9), e43002-e43002 (2019)
Ascorbic acid promotes the stemness of corneal epithelial stem/progenitor cells and accelerates epithelial wound healing in the cornea
Chen J, et al.
Stem Cells Translational Medicine, 6(5), 1356-1365 (2017)

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.