A0788

3-Aminobenzamide

≥99% (TLC)

• 동의어(들): 3-AB, 3-ABA
• Linear Formula: H₂NC₆H₄CONH₂
• CAS Number: 3544-24-9
• Molecular Weight: 136.15
• EC Number: 222-586-9
• MDL number: MFCD00007989
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278206
• NACRES: NA.77

속성

• 분석: ≥99% (TLC)
• 형태: powder
• 색상: white to off-white
• mp: 115-116 °C (lit.)
• solubility: ethanol: 50 mg/mL, clear, light yellow; DMSO: soluble; H₂O: soluble (may require gentle heating)
• 저장 온도: room temp
• SMILES string: NC(=O)c1cccc(N)c1
• InChI: 1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)
• InChI key: GSCPDZHWVNUUFI-UHFFFAOYSA-N
• 유전자 정보: mouse ... Parp1(11545)

설명

애플리케이션

3-Aminobenzamide has been used as a poly-(ADP-ribose) polymerase (PARP) inhibitor in various experimental studies.

생화학적/생리학적 작용

3-Aminobenzamide enhances cell death, unscheduled DNA synthesis and repair replication by interrupting the rejoining of DNA strand breaks induced by both ionizing radiations and several alkylating agents. It has an ability to inhibit the activity of nuclear enzyme poly (ADP-ribose) synthetase (PARS). 3-Aminobenzamide exhibits protective action against myocardial reperfusion injury and local inflammation.

특징 및 장점

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves