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Merck
모든 사진(2)

주요 문서

A3886

Sigma-Aldrich

Aprotinin

powder

동의어(들):

BPTI, Bovine pancreatic trypsin inhibitor, Trasylol, Trypsin inhibitor (basic)

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About This Item

실험식(Hill 표기법):
C284H432N84O79S7
CAS Number:
Molecular Weight:
6511.44
EC Number:
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77

product name

Aprotinin from bovine lung,

생물학적 소스

bovine lung

Quality Level

형태

powder

분자량

~6,500

포장

vial of 15 mg

solubility

glycerol: 3 mg/mL, clear, colorless (equilibration buffer containing 5% glycerol)

UniProt 수납 번호

저장 온도

−20°C

InChI key

ZPNFWUPYTFPOJU-UHFFFAOYSA-N

유전자 정보

cow ... PTI(404172)

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애플리케이션

Aprotinin is largely used as an inhibitor of trypsin.
Gel filtration molecular weight marker

생화학적/생리학적 작용

Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.

단위 정의

One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze 1.0 μmole of N-alpha-benzoyl-DL-arginine p-nitroanilide per minute at pH 7.8 and 25°C. Another commonly used unit is the KIU, with 1 TIU = 1,300 KIU.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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