추천 제품
생물학적 소스
human
Quality Level
분석
≥96% (agarose gel electrophoresis)
양식
lyophilized powder
분자량
monomer calculated mol wt 66478 Da
기술
tissue culture: suitable
불순물
HIV I and HIVII, HCV and HBsAg, tested negative
solubility
H2O: soluble 50 mg/mL
UniProt 수납 번호
외래 활성
Alkaline phosphatase ≤0.001 units/mg protein
Peroxidase ≤0.001 units/mg protein
Protease ≤0.0001 units/mg protein
저장 온도
2-8°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
유전자 정보
human ... ALB(213)
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일반 설명
Albumin is the most copious protein in blood plasma. Produced in the liver, serum albumin serves as a carrier protein for biomolecules like as fatty acids, amino acids, and steroids.
This human serum albumin (HSA) product has been specially tested and evaluated to be low in the following properties:
Serum albumin is used in various applications related to molecular biology, notably as an inert protein stabilizer for stock solutions of enzymes and proteins of interest. In such applications, it is thus important for the HSA to be protease free, to maintain the integrity of the protein or enzyme of interest.
Protease-free HSA is especially useful for applications like:
(b) Nucleic acid hybridization
(c) Radioimmunoassay (RIA)
This human serum albumin (HSA) product has been specially tested and evaluated to be low in the following properties:
- Essentially protease-free / low protease content
- Low alkaline phosphatase content
- Low peroxidase content
Serum albumin is used in various applications related to molecular biology, notably as an inert protein stabilizer for stock solutions of enzymes and proteins of interest. In such applications, it is thus important for the HSA to be protease free, to maintain the integrity of the protein or enzyme of interest.
Protease-free HSA is especially useful for applications like:
- Enzyme assays
- Protein-based assays
- Protease-sensitive techniques such as:
(b) Nucleic acid hybridization
(c) Radioimmunoassay (RIA)
애플리케이션
Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
It was used to test the effect of non-enzymatic glycation on the unfolding of human serum albumin. It was also used to test the two distinct pathways used by intestinal epithelial cells for HLA class II antigen processing.
It was used to test the effect of non-enzymatic glycation on the unfolding of human serum albumin. It was also used to test the two distinct pathways used by intestinal epithelial cells for HLA class II antigen processing.
생화학적/생리학적 작용
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.
특징 및 장점
- Low protease activity / essentially protease-free (≤ 0.0001 units/mg protein)
- Low alkaline phosphatase activity (≤ 0.001 units/mg protein)
- Low peroxidase activity (≤ 0.001 units/mg protein)
제조 메모
Prepared from A1653
기타 정보
View more information on human serum albumin.
면책조항
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
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Human serum albumin (HSA) has pseudoesterase activity. So far on gel specific detection of such property of HSA is never reported. Moreover, protein binding dyes are non-specific for albumin. However, many of such dyes are used for HSA detection. So
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