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Merck
모든 사진(1)

문서

A5843

Sigma-Aldrich

Albumin from human serum

lyophilized powder, low endotoxin

동의어(들):

HSA

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352202
eCl@ss:
42010201
NACRES:
NA.25

생물학적 소스

human

분석

≥96% (agarose gel electrophoresis)

형태

lyophilized powder

분자량

monomer calculated mol wt 66478 Da

불순물

HIV I and HIVII, HCV and HBsAg, tested negative
≤1.0 EU/mg endotoxin

solubility

H2O: soluble 50 mg/mL

UniProt 수납 번호

저장 온도

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

유전자 정보

human ... ALB(213)

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일반 설명

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

애플리케이션

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.

생화학적/생리학적 작용

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.

기타 정보

View more information on human serum albumin.

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves


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