A6419

Adenosine 5′-triphosphate disodium salt hydrate

microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

• 동의어(들): ATP disodium salt
• 실험식(Hill 표기법): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
• CAS Number: 34369-07-8
• Molecular Weight: 551.14 (anhydrous basis)
• MDL number: MFCD00150755
• UNSPSC 코드: 12352207
• eCl@ss: 32160414
• PubChem Substance ID: 24891086
• NACRES: NA.75

속성

• 생물학적 소스: microbial
• Quality Level: 200
• 제품 라인: BioReagent
• 분석: ≥99% (HPLC)
• 형태: powder
• 기술: cell culture | mammalian: suitable
• solubility: H₂O: 50 mg/mL
• 저장 온도: −20°C
• SMILES string: O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
• InChI key: NTBQNWBHIXNPRU-MSQVLRTGSA-L

설명

일반 설명

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

애플리케이션

Adenosine 5′-triphosphate disodium salt hydrate has been used:

• as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
• in inflammasome activation assays in bone marrow derived macrophages
• for the stimulation of macrophages
• in nucleotide synthesis

생화학적/생리학적 작용

P₂ purinergic agonist; increases activity of Ca²⁺-activated K⁺ channels; substrate for ATP-dependent enzyme systems

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type N95 (US)