모든 사진(1)
About This Item
실험식(Hill 표기법):
C35H52N10O9
CAS Number:
Molecular Weight:
756.85
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26
추천 제품
product name
Bradykinin Fragment 1-7, ≥97% (HPLC)
Quality Level
분석
≥97% (HPLC)
형태
powder
색상
white
UniProt 수납 번호
저장 온도
−20°C
SMILES string
NC(CCCNC(N)=N)C(=O)N1CCCC1C(=O)N2CCCC2C(=O)NCC(=O)NC(Cc3ccccc3)C(=O)NC(CO)C(=O)N4CCCC4C(O)=O
InChI
1S/C35H52N10O9/c36-22(10-4-14-39-35(37)38)31(50)44-16-6-12-26(44)33(52)43-15-5-11-25(43)30(49)40-19-28(47)41-23(18-21-8-2-1-3-9-21)29(48)42-24(20-46)32(51)45-17-7-13-27(45)34(53)54/h1-3,8-9,22-27,46H,4-7,10-20,36H2,(H,40,49)(H,41,47)(H,42,48)(H,53,54)(H4,37,38,39)
InChI key
CRROPKNGCGVIOG-UHFFFAOYSA-N
유전자 정보
rat ... Nppa(24602)
Amino Acid Sequence
Arg-Pro-Pro-Gly-Phe-Ser-Pro
일반 설명
Bradykinin fragment 1-7 (BK-(1-7)), an endogenous peptide, is present in plasma.
애플리케이션
Bradykinin Fragment 1-7 has been used as an external calibrant/standard in the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis of protein spots.
Bradykinin Fragment 1-7 is used in research on the specificity and kinetics of kininase(s).
생화학적/생리학적 작용
Bradykinin (BK) is a pro-inflammatory mediator and a neuromediator. It modulates several vascular and renal functions. Bradykinin (BK) plays a key role in inducing vascular permeability and mitogenesis. It helps to activate the liberation of nitric oxide in inflammatory and cancer tissues.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
M Simmaco et al.
Biochimica et biophysica acta, 1033(3), 318-323 (1990-03-26)
The peptide fraction extracted by methanol from the skin of Rana esculenta, a species widely distributed in Western Europe, was investigated. The pharmacological activity found in the extract is attributable to the presence of authentic bradykinin, together with a shorter
L Germain et al.
Journal of neuroimmunology, 13(2), 135-142 (1986-12-01)
The pathology of acute experimental allergic encephalomyelitis is characterized by perivascular cellular infiltrates in the central nervous system. Our hypothesis is that this immuno-pharmacological process can activate the circulating and tissular kallikrein-kinin systems. We studied 21 New Zealand rabbits inoculated
L Germain et al.
Journal of the neurological sciences, 83(2-3), 211-217 (1988-02-01)
Experimental allergic encephalomyelitis (EAE) is a delayed cell-mediated autoimmune reaction to myelin basic protein. The neuropathology of this acute inflammatory process is characterized by cellular infiltration of the perivascular nervous parenchyma which increases the blood-brain barrier permeability. There is good
Darren Greetham et al.
Proteomics, 4(7), 1989-1995 (2004-06-29)
Phage display techniques using random peptide interactions have supported the role of mammalian glutathione transferase (GST) as part of a signalling pathway for both oxidative stress and an apoptosis pathway. Little is known about the interaction of nonmammalian GST with
C Shima et al.
Japanese journal of pharmacology, 60(2), 111-119 (1992-10-01)
Degradation of bradykinin (BK) in human plasma was investigated by searching for a stable metabolite as a marker of kinin release in vivo. BK, incubated with diluted plasma, was degraded to des-Arg9-BK (des-9-BK), des-Phe8-Arg9-BK (des-8,9-BK) and Arg-Pro-Pro-Gly-Phe ([1-5]BK). Des-9-BK was
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.