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Merck
모든 사진(3)

문서

D3126

Sigma-Aldrich

2-Deoxyribose 5-phosphate sodium salt

≥95% (ICP-AES)

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About This Item

실험식(Hill 표기법):
C5H11O7P · xNa+
CAS Number:
Molecular Weight:
214.11 (free acid basis)
MDL number:
UNSPSC 코드:
12352201
PubChem Substance ID:
NACRES:
NA.25

생물학적 소스

synthetic (inorganic)

Quality Level

분석

≥95% (ICP-AES)

형태

powder

색상

white to off-white

solubility

H2O: 100 mg/mL, clear, colorless to very faintly yellow

양이온 미량물

Na: 14.0-19.0% (dry basis)

저장 온도

−20°C

SMILES string

[Na].OC(COP(O)(O)=O)C(O)CC=O

InChI

1S/C5H11O7P.Na.H/c6-2-1-4(7)5(8)3-12-13(9,10)11;;/h2,4-5,7-8H,1,3H2,(H2,9,10,11);;

InChI key

VKWGIGKPYXQSGV-UHFFFAOYSA-N

애플리케이션

2-Deoxyribose 5-phosphate is used as a substrate to identify, differentiate and characterize deoxyribose-phosphate aldolase(s). It is used for the synthesis of 2′-deoxyribonucleoside building blocks for the synthesis of antisense drugs and antiviral nucleosides.

기타 정보

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Anming Wang et al.
Bioprocess and biosystems engineering, 35(5), 857-863 (2012-02-10)
To improve the properties of the immobilised 2-deoxy-D-ribose-5-phosphate aldolase (DERA), unreacted functional groups on support surface were blocked with amino acids. The relative activities of the immobilised enzyme were 144.7 and 141.9% when the post-immobilisation modification was done with Arg
Zhong-Yu You et al.
Journal of industrial microbiology & biotechnology, 40(1), 29-39 (2012-11-28)
A codon-optimized 2-deoxyribose-5-phosphate aldolase (DERA) gene was newly synthesized and expressed in Escherichia coli to investigate its biochemical properties and applications in synthesis of statin intermediates. The expressed DERA was purified and characterized using 2-deoxyribose-5-phosphate as the substrate. The specific
Yong-Mo Kim et al.
Protein expression and purification, 68(2), 196-200 (2009-06-10)
A new deoC gene encoding deoxyribose 5-phosphate aldolase (DERA) was identified in Yersinia sp. EA015 isolated from soil. The DERA gene had an open reading frame (ORF) of 672 base pairs encoding 223 amino acids to yield a protein of
Sanni Voutilainen et al.
Applied microbiology and biotechnology, 104(24), 10515-10529 (2020-11-05)
In this work, deoxyribose-5-phosphate aldolase (Ec DERA, EC 4.1.2.4) from Escherichia coli was chosen as the protein engineering target for improving the substrate preference towards smaller, non-phosphorylated aldehyde donor substrates, in particular towards acetaldehyde. The initial broad set of mutations

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