D3630
Diphenhydramine hydrochloride
≥98% (HPLC)
동의어(들):
2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride, N-(2-Diphenylmethoxyethyl)-N,N-dimethylamine hydrochloride
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모든 사진(4)
About This Item
실험식(Hill 표기법):
C17H21NO · HCl
CAS Number:
Molecular Weight:
291.82
EC Number:
MDL number:
UNSPSC 코드:
12352116
PubChem Substance ID:
NACRES:
NA.77
추천 제품
분석
≥98% (HPLC)
형태
powder
주관자
Johnson & Johnson
SMILES string
Cl[H].CN(C)CCOC(c1ccccc1)c2ccccc2
InChI
1S/C17H21NO.ClH/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;/h3-12,17H,13-14H2,1-2H3;1H
InChI key
PCHPORCSPXIHLZ-UHFFFAOYSA-N
유전자 정보
human ... HRH1(3269)
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
Diphenhydramine hydrochloride has been used:
as a reference compound to study the long duration of action of antihistamine bilastine in vivo
to detect its embryotoxicity by embryonic stem cell test (EST) using cardiomyocyte differentiation and osteoblasts differentiation
as an antihistamine in experimental studies
as a reference compound to study the long duration of action of antihistamine bilastine in vivo
to detect its embryotoxicity by embryonic stem cell test (EST) using cardiomyocyte differentiation and osteoblasts differentiation
as an antihistamine in experimental studies
생화학적/생리학적 작용
H1 histamine receptor antagonist
Diphenhydramine hydrochloride (DPH) is an antihistaminic agent that relieves symptoms of hypersensitive reactions. It exhibits antimuscarinic and marked sedative effects. DPH is also used to prevent nausea, vomiting and vertigo of various causes. In addition, it acts as a potential therapeutic for insomnia.
Diphenhydramine hydrochloride (DPH) is an antihistaminic agent that relieves symptoms of hypersensitive reactions. It exhibits antimuscarinic and marked sedative effects. DPH is also used to prevent nausea, vomiting and vertigo of various causes. In addition, it acts as a potential therapeutic for insomnia.
특징 및 장점
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
![2-[(RS)-(4-Bromophenyl)phenylmethoxy]-N,N-dimethylethanamine hydrochloride pharmaceutical impurity standard](/deepweb/assets/sigmaaldrich/product/structures/287/657/3564cff8-5a0b-40e6-820c-73f2b828efdf/640/3564cff8-5a0b-40e6-820c-73f2b828efdf.png)
Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection
Matty MA, et al.
eLife, 8, e39123-e39123 (2019)
Simultaneous determination of pseudoephedrine hydrochloride and diphenhydramine hydrochloride in cough syrup by gas chromatography (GC)
Raj SV, et al.
Talanta, 46(1), 221-225 (1998)
Alina Tokmakova et al.
iScience, 26(4), 106422-106422 (2023-04-25)
The 25 human bitter taste receptors (TAS2Rs) are expressed on taste and extra-oral cells representing an integrated chemosensory system. The archetypal TAS2R14 is activated by > 150 topographically diverse agonists, raising the question of how this uncharacteristic accommodation is achieved for these
Reevaluation of the embryonic stem cell test
Inselman AL, et al.
International journal of regulatory science, 1(1), 32-49 (2013)
Jiayi Chen et al.
Cell stem cell, 29(11), 1531-1546 (2022-10-21)
The communication between glioblastoma stem cells (GSCs) and the surrounding microenvironment is a prominent feature accounting for the aggressive biology of glioblastoma multiforme (GBM). However, the mechanisms by which GSCs proactively drive interactions with microenvironment is not well understood. In
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