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Merck
모든 사진(1)

주요 문서

D9069

Sigma-Aldrich

N-Desmethyltamoxifen HCl

≥98% (HPLC), solid

동의어(들):

(Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, ICI 55,548

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About This Item

실험식(Hill 표기법):
C25H27NO·HCl
CAS Number:
Molecular Weight:
393.95
MDL number:
UNSPSC 코드:
12352203
PubChem Substance ID:
NACRES:
NA.77

무균

non-sterile

Quality Level

분석

≥98% (HPLC)

양식

solid

저장 조건

desiccated

기술

inhibition assay: suitable

solubility

DMSO: ≥20 mg/mL

배송 상태

ambient

저장 온도

room temp

SMILES string

Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3

InChI

1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;

InChI key

GMLHJWZEYLTNJW-BJFQDICYSA-N

애플리케이션

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

생화학적/생리학적 작용

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

특징 및 장점

This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

픽토그램

Health hazardEnvironment

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

이미 열람한 고객

Slide 1 of 2

1 of 2

Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes
Hackett AR, et al.
Experimental Neurobiology, 308, 72-79 (2018)
Altin Sula et al.
Molecular cell, 81(6), 1160-1169 (2021-01-28)
Voltage-gated sodium channels are targets for many analgesic and antiepileptic drugs whose therapeutic mechanisms and binding sites have been well characterized. We describe the identification of a previously unidentified receptor site within the NavMs voltage-gated sodium channel. Tamoxifen, an estrogen

문서

Protein kinase C (PKC) is an AGC kinase that phosphorylates serine and threonine residues in many target proteins.

We offers many products related to Nuclear Receptors (Steroids) for your research needs.

Chromatograms

application for HPLC

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