G7501
L-Glutamic acid di-tert-butyl ester hydrochloride
≥98%
동의어(들):
L-Glutamic acid 1,5-bis(1,1-dimethylethyl) ester hydrochloride (1:1)
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C13H25NO4 · HCl
CAS Number:
Molecular Weight:
295.80
Beilstein:
3573738
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.26
추천 제품
제품명
L-Glutamic acid di-tert-butyl ester hydrochloride,
분석
≥98%
Quality Level
양식
powder
색상
white
저장 온도
−20°C
SMILES string
Cl[H].[H][C@](N)(CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C
InChI
1S/C13H25NO4.ClH/c1-12(2,3)17-10(15)8-7-9(14)11(16)18-13(4,5)6;/h9H,7-8,14H2,1-6H3;1H/t9-;/m0./s1
InChI key
LFEYMWCCUAOUKZ-FVGYRXGTSA-N
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생화학적/생리학적 작용
Glutamic acid di-tert butyl ester (GTBE) possesses convulsant properties in mice and rats. It might have unique pharmacological features that set it apart from other convulsant medications.
L-Glutamic acid di-tert-butyl ester is C-terminal and R-chain blocked derivative of L-glutamate that may be useful in the synthesis of substance P antagonistic peptides.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
M Antoniou et al.
International journal of peptide and protein research, 40(5), 395-400 (1992-11-01)
Analogues of [Orn6]-SP6-11 have been synthesized in which the methionyl residue is replaced by glutamine gamma-carboxamide substituted derivatives. These analogues where tested in three in vitro preparations representative of NK-1, NK-2 and NK-3 receptor types. Substitution of the SCH3 group
W J Freed et al.
Neurobehavioral toxicology and teratology, 7(3), 275-278 (1985-05-01)
Glutamic acid di-tert butyl ester (GTBE) was found to have a pronounced convulsant effect in mice and rats, producing recurrent clonic convulsions combined with postural and respiratory disturbances in a dosage of 0.5 mmol/kg (148 mg/kg). Tert-butyl ester derivatives of
A Manolopoulou et al.
International journal of peptide and protein research, 41(4), 411-414 (1993-04-01)
Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11-NH2 residue is replaced by the alpha, gamma-dimethyl, alpha, gamma-dibenzyl and alpha, gamma-di-tert-butyl esters of glutamic acid. These analogues were tested in three in vitro preparations representative of NK-1, NK-2 and
Kristina Søborg Pedersen et al.
Molecules (Basel, Switzerland), 25(5) (2020-03-07)
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